@article{b064d394bb0547e9ac969910d13bfa85,
title = "Hypervalent Iodine Mediated Sulfonamide Synthesis",
abstract = "A new metal-free sulfonylation reaction is described. The method takes advantage of the Umpolung reactivity and group-transfer properties of iodine(III) compounds, combining hypervalent iodine reagents and sulfinate salts to deliver a clean and mild transfer of sulfonyl groups to amines and anilines. A total of 25 sulfonamides was synthesised in up to 99 % yield, even on gram-scale. The reaction mechanism was investigated by ESI-MS and DFT calculations.",
keywords = "Hypervalent iodine, Sulfonamides, Synthetic methods, Umpolung",
author = "Poeira, {Diogo L.} and Jo{\~a}o Macara and H{\'e}lio Faustino and Coelho, {Jaime A. S.} and Gois, {Pedro M. P.} and Marques, {M. Manuel B.}",
note = "info:eu-repo/grantAgreement/FCT/5876/147348/PT# info:eu-repo/grantAgreement/FCT/3599-PPCDT/127013/PT# We thank to the FC&T for fellowships PD/BD/142864/2018 and SFRH/BD/116322/2016, SFRH/BPD/100433/2014, SFRH/BPD/102296/2014 and PTDC/QUI-QOR/29967/2017. This work was supported by the Associate Laboratory for Green Chemistry - LAQV which is financed by national funds from FCT/MCTES (UID/QUI/50006/2019). ",
year = "2019",
month = apr,
day = "24",
doi = "10.1002/ejoc.201900259",
language = "English",
volume = "2019",
pages = "2695--2701",
journal = "European Journal of Organic Chemistry",
issn = "1434-193X",
publisher = "Wiley",
number = "15",
}