Humoral Mechanisms of Atherogenesis

Research output: Contribution to conferencePaper

6 Citations (Scopus)

Abstract

The concept that atherosclerosis is an autoimmune disease is no longer controversial. Attention has been paid to cellular immune response, but current research is now focused on the humoral component of this complex disease. Heat shock proteins, oxidized low-density lipoproteins, beta 2-glycoprotein 1, cardiolipins, and, more recently, high-density lipoproteins have been considered to be autoantigens that play a part in atherogenesis. The characterization and understanding of the mechanisms associated with the presence of these antigens and their respective autoantibodies might contribute to elucidating the atherosclerotic process. In the near future, immune modulation might constitute a very effective therapy of atherosclerosis.
Original languageEnglish
Pages401-408
Number of pages8
DOIs
Publication statusPublished - 2009
Event6th International Congress on Autoimmunity Location: Oporto, PORTUGAL Date: SEP 10-14, 2008 -
Duration: 1 Jan 2008 → …

Conference

Conference6th International Congress on Autoimmunity Location: Oporto, PORTUGAL Date: SEP 10-14, 2008
Period1/01/08 → …

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    Batuca, J., Amaral, M., & Alves, J. D. (2009). Humoral Mechanisms of Atherogenesis. 401-408. Paper presented at 6th International Congress on Autoimmunity Location: Oporto, PORTUGAL Date: SEP 10-14, 2008, . https://doi.org/10.1111/j.1749-6632.2009.04747.x