TY - JOUR
T1 - Histopathological baseline levels and confounding factors in common sole (Solea solea) for marine environmental risk assessment
AU - Cuevas, N.
AU - Zorita, I.
AU - Costa, P.M.
AU - Larreta, J.
AU - Franco, J.
N1 - sem PDF conforme despacho.
Spanish Ministry of Economy and Competitiveness through FISHEALTH project - CTM-2012-40203-C02-02;
Portuguese Foundation for Science and Technology - (SFRH/BPD/72564/2010).
PY - 2015/9/1
Y1 - 2015/9/1
N2 - Liver and gonad histopathology, biometric parameters and hepatic metal bioaccumulation were assessed monthly over a one-year period in common soles from the Basque continental shelf, in order to determine baseline levels and confounding factors within biomonitoring studies. Biometric parameters and hepatic metal bioaccumulation varied according to season and gender. Accordingly, hepatic histopathological traits presented seasonal variations related to the reproductive cycle. However, the hepatic histopathological index showed that seasonality and gender were not significant confounding factors. Conversely, the gonad histopathological index was modulated by season and gender. As for organ comparison, the liver endured more severe histopathological damage than the gonad. In brief, the sampling period and gender may not affect the estimation of hepatic histopathological indices for biomonitoring purposes. Nonetheless, due to different sensitivities to environmental 'noise' variables, the sampling period and gender differentiation should be thoroughly considered for the assessment of gonad histopathology, biometrics and metal bioaccumulation.
AB - Liver and gonad histopathology, biometric parameters and hepatic metal bioaccumulation were assessed monthly over a one-year period in common soles from the Basque continental shelf, in order to determine baseline levels and confounding factors within biomonitoring studies. Biometric parameters and hepatic metal bioaccumulation varied according to season and gender. Accordingly, hepatic histopathological traits presented seasonal variations related to the reproductive cycle. However, the hepatic histopathological index showed that seasonality and gender were not significant confounding factors. Conversely, the gonad histopathological index was modulated by season and gender. As for organ comparison, the liver endured more severe histopathological damage than the gonad. In brief, the sampling period and gender may not affect the estimation of hepatic histopathological indices for biomonitoring purposes. Nonetheless, due to different sensitivities to environmental 'noise' variables, the sampling period and gender differentiation should be thoroughly considered for the assessment of gonad histopathology, biometrics and metal bioaccumulation.
KW - Basque continental shelf
KW - Flatfish
KW - Histopathology
KW - Metal bioaccumulation
KW - Reference values
KW - Seasonality
UR - http://www.scopus.com/inward/record.url?scp=84942191599&partnerID=8YFLogxK
U2 - 10.1016/j.marenvres.2015.09.002
DO - 10.1016/j.marenvres.2015.09.002
M3 - Article
C2 - 26364682
AN - SCOPUS:84942191599
SN - 0141-1136
VL - 110
SP - 162
EP - 173
JO - Marine Environmental Research
JF - Marine Environmental Research
ER -