High rate of detection of G8P[6] rotavirus in children with acute gastroenteritis in São Tomé and Príncipe

Claudia Istrate, Sumit Sharma, Johan Nordgren, Sandra Videira e Castro, Ângela Lopes, João Piedade, Ahmed Zaky, António Lima, Edgar Neves, José Veiga, Aida Esteves

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

The burden of rotavirus infections greatly affects the low-income African countries. In the absence of epidemiological data on pediatric diarrhea in São Tomé and Príncipe (STP), a study was conducted from August to December 2011. Rotavirus antigen was detected in 36.7 % of the collected fecal samples (87/237). G8P[6] was identified as the predominant genotype (71.1 % detection rate), while G1P[8] represented only 8.4 %. Phylogenetic analysis of VP7 G8 strains showed clustering within lineage G8d, while VP4 P[6] strains clustered within lineage 1a. Our results represent the first report on rotavirus from STP and show one of the highest detection rates of G8 rotaviruses worldwide.

Original languageEnglish
Pages (from-to)423-428
Number of pages6
JournalArchives of Virology
Volume160
Issue number2
DOIs
Publication statusPublished - 2015

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