High rate of detection of G8P[6] rotavirus in children with acute gastroenteritis in São Tomé and Príncipe

Claudia Istrate; Sumit Sharma; Johan Nordgren; Sandra Videira e Castro; Ângela Lopes; João Piedade; Ahmed Zaky; António Lima; Edgar Neves; José Veiga; Aida Esteves

doi:10.1007/s00705-014-2244-7

High rate of detection of G8P[6] rotavirus in children with acute gastroenteritis in São Tomé and Príncipe

Claudia Istrate, Sumit Sharma, Johan Nordgren, Sandra Videira e Castro, Ângela Lopes, João Piedade, Ahmed Zaky, António Lima, Edgar Neves, José Veiga, Aida Esteves

Instituto de Higiene e Medicina Tropical (IHMT)

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The burden of rotavirus infections greatly affects the low-income African countries. In the absence of epidemiological data on pediatric diarrhea in São Tomé and Príncipe (STP), a study was conducted from August to December 2011. Rotavirus antigen was detected in 36.7 % of the collected fecal samples (87/237). G8P[6] was identified as the predominant genotype (71.1 % detection rate), while G1P[8] represented only 8.4 %. Phylogenetic analysis of VP7 G8 strains showed clustering within lineage G8d, while VP4 P[6] strains clustered within lineage 1a. Our results represent the first report on rotavirus from STP and show one of the highest detection rates of G8 rotaviruses worldwide.

Original language	English
Pages (from-to)	423-428
Number of pages	6
Journal	Archives of Virology
Volume	160
Issue number	2
DOIs	https://doi.org/10.1007/s00705-014-2244-7
Publication status	Published - 2015

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title = "High rate of detection of G8P[6] rotavirus in children with acute gastroenteritis in S{\~a}o Tom{\'e} and Pr{\'i}ncipe",

abstract = "The burden of rotavirus infections greatly affects the low-income African countries. In the absence of epidemiological data on pediatric diarrhea in S{\~a}o Tom{\'e} and Pr{\'i}ncipe (STP), a study was conducted from August to December 2011. Rotavirus antigen was detected in 36.7 % of the collected fecal samples (87/237). G8P[6] was identified as the predominant genotype (71.1 % detection rate), while G1P[8] represented only 8.4 %. Phylogenetic analysis of VP7 G8 strains showed clustering within lineage G8d, while VP4 P[6] strains clustered within lineage 1a. Our results represent the first report on rotavirus from STP and show one of the highest detection rates of G8 rotaviruses worldwide.",

author = "Claudia Istrate and Sumit Sharma and Johan Nordgren and {Videira e Castro}, Sandra and {\^A}ngela Lopes and Jo{\~a}o Piedade and Ahmed Zaky and Ant{\'o}nio Lima and Edgar Neves and Jos{\'e} Veiga and Aida Esteves",

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doi = "10.1007/s00705-014-2244-7",

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T1 - High rate of detection of G8P[6] rotavirus in children with acute gastroenteritis in São Tomé and Príncipe

AU - Istrate, Claudia

AU - Sharma, Sumit

AU - Nordgren, Johan

AU - Videira e Castro, Sandra

AU - Lopes, Ângela

AU - Piedade, João

AU - Zaky, Ahmed

AU - Lima, António

AU - Neves, Edgar

AU - Veiga, José

AU - Esteves, Aida

N1 - PMID: 25283609 WOS:000349433500006

PY - 2015

Y1 - 2015

N2 - The burden of rotavirus infections greatly affects the low-income African countries. In the absence of epidemiological data on pediatric diarrhea in São Tomé and Príncipe (STP), a study was conducted from August to December 2011. Rotavirus antigen was detected in 36.7 % of the collected fecal samples (87/237). G8P[6] was identified as the predominant genotype (71.1 % detection rate), while G1P[8] represented only 8.4 %. Phylogenetic analysis of VP7 G8 strains showed clustering within lineage G8d, while VP4 P[6] strains clustered within lineage 1a. Our results represent the first report on rotavirus from STP and show one of the highest detection rates of G8 rotaviruses worldwide.

AB - The burden of rotavirus infections greatly affects the low-income African countries. In the absence of epidemiological data on pediatric diarrhea in São Tomé and Príncipe (STP), a study was conducted from August to December 2011. Rotavirus antigen was detected in 36.7 % of the collected fecal samples (87/237). G8P[6] was identified as the predominant genotype (71.1 % detection rate), while G1P[8] represented only 8.4 %. Phylogenetic analysis of VP7 G8 strains showed clustering within lineage G8d, while VP4 P[6] strains clustered within lineage 1a. Our results represent the first report on rotavirus from STP and show one of the highest detection rates of G8 rotaviruses worldwide.

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SN - 0304-8608

VL - 160

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JO - Archives of Virology

JF - Archives of Virology

IS - 2

ER -

High rate of detection of G8P[6] rotavirus in children with acute gastroenteritis in São Tomé and Príncipe

Abstract

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