TY - JOUR
T1 - High prevalence of biocide resistance determinants in Staphylococcus aureus isolates from three African countries
AU - Conceição, Teresa
AU - Coelho, Céline
AU - De Lencastre, Hermínia
AU - Aires-De-Sousa, Marta
PY - 2016/1/1
Y1 - 2016/1/1
N2 - We assessed the prevalence of six biocide resistance genes among 82 methicillin-resistant Staphylococcus aureus (MRSA) and 219 methicillin-susceptible S. aureus (MSSA) isolates from three African countries; the prevalence was very high for sepA (95.3%), mepA (89.4%), and norA (86.4%), intermediate for lmrS (60.8%) and qacAB (40.5%), and low for smr (3.7%). A significant association between biocide resistance genes and antibiotic resistance was observed, and a new cutoff MIC of ≥1 mg/liter for chlorhexidine nonsusceptibility was defined.
AB - We assessed the prevalence of six biocide resistance genes among 82 methicillin-resistant Staphylococcus aureus (MRSA) and 219 methicillin-susceptible S. aureus (MSSA) isolates from three African countries; the prevalence was very high for sepA (95.3%), mepA (89.4%), and norA (86.4%), intermediate for lmrS (60.8%) and qacAB (40.5%), and low for smr (3.7%). A significant association between biocide resistance genes and antibiotic resistance was observed, and a new cutoff MIC of ≥1 mg/liter for chlorhexidine nonsusceptibility was defined.
UR - http://www.scopus.com/inward/record.url?scp=84957894491&partnerID=8YFLogxK
U2 - 10.1128/AAC.02140-15
DO - 10.1128/AAC.02140-15
M3 - Article
AN - SCOPUS:84957894491
SN - 0066-4804
VL - 60
SP - 678
EP - 681
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 1
ER -
