As Trombofilias Hereditárias na Grávida: do Risco Trombótico ao Sucesso da Gravidez

Translated title of the contribution: Hereditary Thrombophilia and Pregnancy: Thrombotic Risk and Pregnancy Outcome

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Abstract

Thromboembolic disease and obstetric complications related to ischemia of the placenta are currently the major causes of maternal mortality and morbidity. Thrombophilia been implicated in their aetiology and the magnitude of the risk depends on the type of thrombophilia. As the evidence is still unclear and controversial, questions about the clinical management of pregnant women with thrombophilia are a daily issue. We aim to review, bearing in mind the consensus and controversies, the impact of inherited thrombophilia in the risk of thrombosis related to pregnancy and of obstetric complications. Moreover, the diagnostic, preventive and therapeutic approach during pregnancy and puerperium, including the role of antithrombotic pharmacopoeia available, will be discussed.
Original languagePortuguese
Pages (from-to)433-441
Number of pages9
JournalActa medica portuguesa
Volume25
Issue number6
Publication statusPublished - Nov 2012

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