Hepatitis delta virus: a peculiar virus.

Carolina Alves, Cristina Branco, Celso Vladimiro Ferreira de Abreu Cunha

Research output: Contribution to journalBook/Film/Article reviewpeer-review

23 Citations (Scopus)
4 Downloads (Pure)


The hepatitis delta virus (HDV) is distributed worldwide and related to the most severe form of viral hepatitis. HDV is a satellite RNA virus dependent on hepatitis B surface antigens to assemble its envelope and thus form new virions and propagate infection. HDV has a small 1.7 Kb genome making it the smallest known human virus. This deceivingly simple virus has unique biological features and many aspects of its life cycle remain elusive. The present review endeavors to gather the available information on HDV epidemiology and clinical features as well as HDV biology.
Original languageEnglish
Article number560105
JournalAdvances In Virology
Publication statusPublished - 1 Jan 2013


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