Abstract
The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted development in exploring biomolecular interactions with AuNPscontaining systems, pursuing biomedical applications in diagnostics. Among these applications, AuNPs have been remarkably useful for the development of DNA/RNA detection and characterization systems for diagnostics, including systems suitable for point of need. Here, emphasis will be on available molecular detection schemes of relevant pathogens and their molecular characterization, genomic sequences associated with medical conditions (including cancer), mutation and polymorphism identification, and the quantification of gene expression.
| Original language | English |
|---|---|
| Title of host publication | Handbook of Nanoparticles |
| Publisher | SPRINGER INTERNATIONAL PUBLISHING AG |
| Pages | 1339-1370 |
| Number of pages | 32 |
| ISBN (Electronic) | 9783319153384 |
| ISBN (Print) | 9783319153377 |
| DOIs | |
| Publication status | Published - 18 Sep 2015 |
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Keywords
- Au-nanobeacons
- Au-nanoprobes
- LSPR
- Nucleic acid
- Pathogen
- Point of care
- SNP
Cite this
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Gold nanoparticles for DNA/RNA-based diagnostics. / Franco, Ricardo; Pedrosa, Pedro; Carlos, Fábio Ferreira; Veigas, Bruno; Baptista, Pedro Miguel Ribeiro Viana.
Handbook of Nanoparticles. SPRINGER INTERNATIONAL PUBLISHING AG, 2015. p. 1339-1370.Research output: Chapter in Book/Report/Conference proceeding › Chapter
TY - CHAP
T1 - Gold nanoparticles for DNA/RNA-based diagnostics
AU - Franco, Ricardo
AU - Pedrosa, Pedro
AU - Carlos, Fábio Ferreira
AU - Veigas, Bruno
AU - Baptista, Pedro Miguel Ribeiro Viana
PY - 2015/9/18
Y1 - 2015/9/18
N2 - The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted development in exploring biomolecular interactions with AuNPscontaining systems, pursuing biomedical applications in diagnostics. Among these applications, AuNPs have been remarkably useful for the development of DNA/RNA detection and characterization systems for diagnostics, including systems suitable for point of need. Here, emphasis will be on available molecular detection schemes of relevant pathogens and their molecular characterization, genomic sequences associated with medical conditions (including cancer), mutation and polymorphism identification, and the quantification of gene expression.
AB - The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted development in exploring biomolecular interactions with AuNPscontaining systems, pursuing biomedical applications in diagnostics. Among these applications, AuNPs have been remarkably useful for the development of DNA/RNA detection and characterization systems for diagnostics, including systems suitable for point of need. Here, emphasis will be on available molecular detection schemes of relevant pathogens and their molecular characterization, genomic sequences associated with medical conditions (including cancer), mutation and polymorphism identification, and the quantification of gene expression.
KW - Au-nanobeacons
KW - Au-nanoprobes
KW - LSPR
KW - Nucleic acid
KW - Pathogen
KW - Point of care
KW - SNP
UR - http://www.scopus.com/inward/record.url?scp=84955348211&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-15338-4_31
DO - 10.1007/978-3-319-15338-4_31
M3 - Chapter
SN - 9783319153377
SP - 1339
EP - 1370
BT - Handbook of Nanoparticles
PB - SPRINGER INTERNATIONAL PUBLISHING AG
ER -