TY - JOUR
T1 - Gold nanoparticles for diagnostics
T2 - Advances towards points of care
AU - Cordeiro, Milton
AU - Pedrosa, Pedro
AU - Carlos, Fábio Ferreira
AU - Lopez, António
AU - Baptista, Pedro Viana
N1 - The authors acknowledge Fundacao para a Ciencia e Tecnologia (FCT/MEC) for funding: REQUIMTE (Pest-C/EQB/LA0006/2011); UCIBIO (UID/Multi/04378/2013); SFRH/BD/87836/2012 for MC; PD/BD/105734/2014 for PP. WaterJPI/0003/2013-TRACE for FFC.
PY - 2016/12
Y1 - 2016/12
N2 - The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted developments in the exploration of biomolecular interactions with AuNP-containing systems, in particular for biomedical applications in diagnostics. These systems show great promise in improving sensitivity, ease of operation and portability. Despite this endeavor, most platforms have yet to reach maturity and make their way into clinics or points of care (POC). Here, we present an overview of emerging and available molecular diagnostics using AuNPs for biomedical sensing that are currently being translated to the clinical setting.
AB - The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted developments in the exploration of biomolecular interactions with AuNP-containing systems, in particular for biomedical applications in diagnostics. These systems show great promise in improving sensitivity, ease of operation and portability. Despite this endeavor, most platforms have yet to reach maturity and make their way into clinics or points of care (POC). Here, we present an overview of emerging and available molecular diagnostics using AuNPs for biomedical sensing that are currently being translated to the clinical setting.
KW - Biomolecular sensing
KW - Diagnosis
KW - Gold nanoparticles
KW - Point-of-need
UR - http://www.scopus.com/inward/record.url?scp=85026449952&partnerID=8YFLogxK
U2 - 10.3390/diagnostics6040043
DO - 10.3390/diagnostics6040043
M3 - Review article
C2 - 27879660
AN - SCOPUS:85026449952
VL - 6
JO - Diagnostics
JF - Diagnostics
IS - 4
M1 - 43
ER -