TY - JOUR
T1 - Gold Nanoparticles as (Bio)Chemical Sensors
AU - Peixoto de Almeida, Miguel
AU - Pereira, Eulália
AU - Baptista, Pedro
AU - Gomes, Inês
AU - Figueiredo, Sara
AU - Soares, Leonor
AU - Franco, Ricardo
PY - 2014
Y1 - 2014
N2 - This chapter focuses on several sensing strategies and major recent advances in the use of gold nanoparticles in (bio)sensing of chemical and biological analytes. A brief introduction is presented on relevant properties of gold nanoparticles for sensing, the main types of (bio)chemical sensors, and the main detection techniques, followed by subsections according to sensing methodologies. These include colorimetric sensing and the biobarcode assay, fluorometric-based methods, electric and electrochemical sensing, and, last, more recent and advanced methodologies such as surface plasmon resonance and Raman-based sensors. In closing, relevance is given to advanced methods, featuring extremely high sensitivity and selectivity, down to single-molecule detection. Anisotropic gold nanoparticles have a special role in future developments.
AB - This chapter focuses on several sensing strategies and major recent advances in the use of gold nanoparticles in (bio)sensing of chemical and biological analytes. A brief introduction is presented on relevant properties of gold nanoparticles for sensing, the main types of (bio)chemical sensors, and the main detection techniques, followed by subsections according to sensing methodologies. These include colorimetric sensing and the biobarcode assay, fluorometric-based methods, electric and electrochemical sensing, and, last, more recent and advanced methodologies such as surface plasmon resonance and Raman-based sensors. In closing, relevance is given to advanced methods, featuring extremely high sensitivity and selectivity, down to single-molecule detection. Anisotropic gold nanoparticles have a special role in future developments.
KW - (Bio)chemical sensor
KW - Anisotropic nanoparticles
KW - Bioassay
KW - DNA
KW - Gold nanoparticles
KW - Immunoassay
UR - http://www.scopus.com/inward/record.url?scp=84908205752&partnerID=8YFLogxK
U2 - 10.1016/B978-0-444-63285-2.00013-4
DO - 10.1016/B978-0-444-63285-2.00013-4
M3 - Article
AN - SCOPUS:84908205752
SN - 0166-526X
VL - 66
SP - 529
EP - 567
JO - Comprehensive Analytical Chemistry
JF - Comprehensive Analytical Chemistry
ER -