Gestational diabetes mellitus complicating twin pregnancies

Teresinha Simões, A. Queirós, L. Correia, Tiago Rocha, E. Dias, I. Blickstein

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27 Citations (Scopus)


Objective: To compare outcomes of twin pregnancies with and without gestational diabetes mellitus (GDM). Study design: We compared 105 twin pregnancies with GDM (7.8% of all twin pregnancies) to 315 controls without GDM, matched for gestational age, chorionicity and year of birth. Results: Pre-gravid obesity appears to predispose women to GDM during twin pregnancy wodds ratio (OR) 3.5; 95% confidence interval (CI) 1.7, 7.0]. Overweight and obese women that subsequently developed GDM during their twin gestation were less likely to conceive spontaneously (OR 0.4; 95% CI 0.3, 0.7). Twins from the GDM group had more respiratory distress syndrome (RDS, OR 2.2; 95% CI 1.3, 3.7) and had a three-fold, but not significantly increased perinatal mortality rate. Birth weight characteristics were similar in both groups. Conclusion: Twin pregnancies complicated by GDM might be associated with pre-pregnancy maternal obesity and are at increased risk of RDS and non-significant increased risk of perinatal death.
Original languageEnglish
Pages (from-to)437-440
JournalJournal Of Perinatal Medicine
Issue number4
Publication statusPublished - 1 Jul 2011


  • Gestational diabetes
  • obesity
  • respiratory distress syndrome
  • twin pregnancy


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