TY - JOUR
T1 - Genome Characterization and Spaciotemporal Dispersal Analysis of Bagaza Virus Detected in Portugal, 2021
AU - Falcão, Marta
AU - Barros, Margarida
AU - Duarte, Margarida D.
AU - Santos, Fábio Abade dos
AU - Fagulha, Teresa
AU - Henriques, Margarida
AU - Ramos, Fernanda
AU - Duarte, Ana
AU - Luís, Tiago
AU - Parreira, Ricardo
AU - Barros, Sílvia C.
N1 - Funding Information:
This work received financial support from the Global Health and Tropical Medicine Center (which is funded through Fundação para a Ciência e a Tecnologia (FCT) contract UID/Multi/04413/2013). This research was also funded by FCT, Project UIDB/00276/2020 and LA/P/0059/2020-AL4AnimalS, and by the Interdisciplinary Research Center on Animal Health (CIISA), Faculty of Veterinary Medicine, University of Lisbon (Portugal). Finally, this research was also partially funded by the Interdisciplinary Research Center on Animal Health (Project CIISA-INOV 4/2021), Faculty of Veterinary Medicine, University of Lisbon (CIISA, FMV-UL) (Portugal).
Publisher Copyright:
© 2023 by the authors.
PY - 2023/2
Y1 - 2023/2
N2 - In September 2021, Bagaza virus (BAGV), a member of the Ntaya group from the Flavivirus genus, was detected for the first time in Portugal, in the heart and the brain of a red-legged partridge found dead in a hunting ground in Serpa (Alentejo region; southern Portugal). Here we report the genomic characterization of the full-length sequence of the BAGV detected (BAGV/PT/2021), including phylogenetic reconstructions and spaciotemporal analyses. Phylogenies inferred from nucleotide sequence alignments, complemented with the analysis of amino acid alignments, indicated that the BAGV strain from Portugal is closely related to BAGV strains previously detected in Spain, suggesting a common ancestor that seems to have arrived in the Iberia Peninsula in the late 1990s to early 2000s. In addition, our findings support previous observations that BAGV and Israel turkey meningoencephalitis virus (ITV) belong to the same viral species.
AB - In September 2021, Bagaza virus (BAGV), a member of the Ntaya group from the Flavivirus genus, was detected for the first time in Portugal, in the heart and the brain of a red-legged partridge found dead in a hunting ground in Serpa (Alentejo region; southern Portugal). Here we report the genomic characterization of the full-length sequence of the BAGV detected (BAGV/PT/2021), including phylogenetic reconstructions and spaciotemporal analyses. Phylogenies inferred from nucleotide sequence alignments, complemented with the analysis of amino acid alignments, indicated that the BAGV strain from Portugal is closely related to BAGV strains previously detected in Spain, suggesting a common ancestor that seems to have arrived in the Iberia Peninsula in the late 1990s to early 2000s. In addition, our findings support previous observations that BAGV and Israel turkey meningoencephalitis virus (ITV) belong to the same viral species.
KW - Alectoris rufa
KW - BAGV
KW - Flavivirus
KW - genome
KW - Israel turkey meningoencephalomyelitis virus (ITV)
KW - Ntaya group
KW - phylogenetic analysis
KW - spaciotemporal analyses
UR - http://www.scopus.com/inward/record.url?scp=85148722897&partnerID=8YFLogxK
U2 - 10.3390/pathogens12020150
DO - 10.3390/pathogens12020150
M3 - Article
C2 - 36839422
AN - SCOPUS:85148722897
SN - 2076-0817
VL - 12
JO - Pathogens
JF - Pathogens
IS - 2
M1 - 150
ER -
