Generation and biological evaluation of the products formed from the exposure of Phenothiazine to a 266 nm laser beam

T. Alexandru; M. L. Pascu; B. Danko; V. Nastasa; M. Boni; A. Militaru; I. R. Andrei; A. Staicu; A. Hunyadi; A. Armada; M. Viveiros; L. Amaral

doi:10.1117/12.2032666

Generation and biological evaluation of the products formed from the exposure of Phenothiazine to a 266 nm laser beam

T. Alexandru, M. L. Pascu, B. Danko, V. Nastasa, M. Boni, A. Militaru, I. R. Andrei, A. Staicu, A. Hunyadi, A. Armada, M. Viveiros, L. Amaral

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Citations (Scopus)

Abstract

Phenothiazine exposed to white light or UV radiation undergoes a variety of reactions that result in the degradation of the parental compound and the formation of new species. Chlorpromazine exposed to the 266 nm laser beam of given energy levels yielded species derived from it, whose number increased with the exposure duration. At distinct time intervals the irradiation products were evaluated by spectrophotometry between 200-1500 nm, Thin Layer Chromatography, and for antimicrobial activity of Chlorpromazine against different test organisms such as Staphylococcus aureus.

Original language	English
Title of host publication	Proc. SPIE 8882, ROMOPTO 2012 - Tenth Conference on Optics: Micro- to Nanophotonics III
Number of pages	8
Volume	88820T
DOIs	https://doi.org/10.1117/12.2032666
Publication status	Published - 10 Jun 2013
Event	10th Conference on Optics: Micro- to Nanophotonics III, ROMOPTO 2012 - Bucharest Duration: 3 Sept 2013 → 6 Sept 2013

Conference

Conference	10th Conference on Optics: Micro- to Nanophotonics III, ROMOPTO 2012
City	Bucharest
Period	3/09/13 → 6/09/13

Keywords

absorption spectroscopy
Chlorpromazine
CPZ
photo-degradation.
Promazine
PZ
TLC

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1117/12.2032666

Cite this

Alexandru, T., Pascu, M. L., Danko, B., Nastasa, V., Boni, M., Militaru, A., Andrei, I. R., Staicu, A., Hunyadi, A., Armada, A., Viveiros, M., & Amaral, L. (2013). Generation and biological evaluation of the products formed from the exposure of Phenothiazine to a 266 nm laser beam. In Proc. SPIE 8882, ROMOPTO 2012 - Tenth Conference on Optics: Micro- to Nanophotonics III (Vol. 88820T). Article 88820T https://doi.org/10.1117/12.2032666

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title = "Generation and biological evaluation of the products formed from the exposure of Phenothiazine to a 266 nm laser beam",

abstract = "Phenothiazine exposed to white light or UV radiation undergoes a variety of reactions that result in the degradation of the parental compound and the formation of new species. Chlorpromazine exposed to the 266 nm laser beam of given energy levels yielded species derived from it, whose number increased with the exposure duration. At distinct time intervals the irradiation products were evaluated by spectrophotometry between 200-1500 nm, Thin Layer Chromatography, and for antimicrobial activity of Chlorpromazine against different test organisms such as Staphylococcus aureus.",

keywords = "absorption spectroscopy, Chlorpromazine, CPZ, photo-degradation., Promazine, PZ, TLC",

author = "T. Alexandru and Pascu, {M. L.} and B. Danko and V. Nastasa and M. Boni and A. Militaru and Andrei, {I. R.} and A. Staicu and A. Hunyadi and A. Armada and M. Viveiros and L. Amaral",

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doi = "10.1117/12.2032666",

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volume = "88820T",

booktitle = "Proc. SPIE 8882, ROMOPTO 2012 - Tenth Conference on Optics: Micro- to Nanophotonics III",

note = "10th Conference on Optics: Micro- to Nanophotonics III, ROMOPTO 2012 ; Conference date: 03-09-2013 Through 06-09-2013",

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Alexandru, T, Pascu, ML, Danko, B, Nastasa, V, Boni, M, Militaru, A, Andrei, IR, Staicu, A, Hunyadi, A, Armada, A , Viveiros, M & Amaral, L 2013, Generation and biological evaluation of the products formed from the exposure of Phenothiazine to a 266 nm laser beam. in Proc. SPIE 8882, ROMOPTO 2012 - Tenth Conference on Optics: Micro- to Nanophotonics III. vol. 88820T, 88820T, 10th Conference on Optics: Micro- to Nanophotonics III, ROMOPTO 2012, Bucharest, 3/09/13. https://doi.org/10.1117/12.2032666

Generation and biological evaluation of the products formed from the exposure of Phenothiazine to a 266 nm laser beam. / Alexandru, T.; Pascu, M. L.; Danko, B. et al.
Proc. SPIE 8882, ROMOPTO 2012 - Tenth Conference on Optics: Micro- to Nanophotonics III. Vol. 88820T 2013. 88820T.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Generation and biological evaluation of the products formed from the exposure of Phenothiazine to a 266 nm laser beam

AU - Alexandru, T.

AU - Pascu, M. L.

AU - Danko, B.

AU - Nastasa, V.

AU - Boni, M.

AU - Militaru, A.

AU - Andrei, I. R.

AU - Staicu, A.

AU - Hunyadi, A.

AU - Armada, A.

AU - Viveiros, M.

AU - Amaral, L.

PY - 2013/6/10

Y1 - 2013/6/10

N2 - Phenothiazine exposed to white light or UV radiation undergoes a variety of reactions that result in the degradation of the parental compound and the formation of new species. Chlorpromazine exposed to the 266 nm laser beam of given energy levels yielded species derived from it, whose number increased with the exposure duration. At distinct time intervals the irradiation products were evaluated by spectrophotometry between 200-1500 nm, Thin Layer Chromatography, and for antimicrobial activity of Chlorpromazine against different test organisms such as Staphylococcus aureus.

AB - Phenothiazine exposed to white light or UV radiation undergoes a variety of reactions that result in the degradation of the parental compound and the formation of new species. Chlorpromazine exposed to the 266 nm laser beam of given energy levels yielded species derived from it, whose number increased with the exposure duration. At distinct time intervals the irradiation products were evaluated by spectrophotometry between 200-1500 nm, Thin Layer Chromatography, and for antimicrobial activity of Chlorpromazine against different test organisms such as Staphylococcus aureus.

KW - absorption spectroscopy

KW - Chlorpromazine

KW - CPZ

KW - photo-degradation.

KW - Promazine

KW - PZ

KW - TLC

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UR - https://www.researchgate.net/publication/257029127_Generation_and_biological_evaluation_of_the_products_formed_from_the_exposure_of_Phenothiazine_to_a_266_nm_laser_beam

U2 - 10.1117/12.2032666

DO - 10.1117/12.2032666

M3 - Conference contribution

AN - SCOPUS:84883591171

SN - 9780819497444

VL - 88820T

BT - Proc. SPIE 8882, ROMOPTO 2012 - Tenth Conference on Optics: Micro- to Nanophotonics III

T2 - 10th Conference on Optics: Micro- to Nanophotonics III, ROMOPTO 2012

Y2 - 3 September 2013 through 6 September 2013

ER -

Generation and biological evaluation of the products formed from the exposure of Phenothiazine to a 266 nm laser beam

Abstract

Conference

Keywords

UN SDGs

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