Abstract
Gellan gum (GG) is a natural, negatively charged exopolysaccharide constituted by a tetrasaccharide structure of glucose, glucuronic acid, and rhamnose units. It is available in two forms, high acyl and low acyl GG, and has been applied in the production of several materials, from hydrogels to microspheres. The growing interest in GG microspheres in pharmacy and biomedicine reinforces their ability as an efficient matrix for tissue engineering and drug delivery systems. Among the popular GG characteristics, the biocompatibility, mucoadhesive capacity, gelling, malleability, and versatile texture remain the most attractive. This chapter summarizes the characteristics and preparation procedures for GG microspheres’ production as well as a comprehensive discussion on both microspheres’ applicability in the biomedical field and on current efforts of its suitable translation to industry.
| Original language | English |
|---|---|
| Title of host publication | Application of Gellan Gum as a Biomedical Polymer |
| Editors | Amit Kumar Nayak, Md Saquib Hasnain |
| Place of Publication | London |
| Publisher | Elsevier |
| Chapter | 8 |
| Pages | 145-169 |
| Number of pages | 25 |
| ISBN (Electronic) | 978-0-323-91815-2 |
| ISBN (Print) | 978-032397243-7 |
| DOIs | |
| Publication status | Published - 1 Jan 2024 |
Keywords
- drug delivery
- Gellan gum
- industry
- pharmaceutical and biomedical research
- tissue engineering