Functional evaluation of coronary disease by CT angiography

Pedro De Araújo Gonçalves, Gastón A. Rodríguez-Granillo, Ernest Spitzer, Pannipa Suwannasom, Christian Loewe, Koen Nieman, Hector M. Garcia-Garcia

Research output: Contribution to journalReview articlepeer-review

24 Citations (Scopus)
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In recent years, several technical developments in the field of cardiac computed tomography (CT) have made possible the extraction of functional information from an anatomy-based examination. Several different lines have been explored and will be reviewed in the present paper, namely: 1) myocardial perfusion imaging; 2) transluminal attenuation gradients and corrected coronary opacification indexes; 3) fractional flow reserve computed from CT; and 4) extrapolation from atherosclerotic plaque characteristics. In view of these developments, cardiac CT has the potential to become in the near future a truly 2-in-1 noninvasive evaluation for coronary artery disease.

Original languageEnglish
Pages (from-to)1322-1335
Number of pages14
JournalJacc: Cardiovascular Imaging
Issue number11
Publication statusPublished - Nov 2015


  • cardiac computed tomography
  • coronary artery disease
  • functional evaluation


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