Abstract
Subjective cognitive complaints (SCCs) are frequent in the elderly population. The majority of individuals with subjective complaints never progress to significant cognitive decline, but some of them have a higher risk of progression to objective cognitive impairment than persons with no cognitive concerns. We performed a systematic review of community-based studies that focused on the progression risk associated with SCC and on the complainers’ characteristics associated with progression. Seventeen studies were included. As a group, SCCs are associated with a significantly higher risk of progression to dementia. Worried complainers, persons who refer an impact of their complaints on activities of daily living, and those whose complaints are also noticed by an informant have the highest risk of progression. Taking into account the fluctuating course of SCC and their frequent reversion, care should be taken to not overvaluate them. Further studies are necessary to better define risk features.
| Original language | English |
|---|---|
| Pages (from-to) | 105-14 |
| Number of pages | 10 |
| Journal | American journal of Alzheimer's disease and other dementias |
| Volume | 31 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Mar 2016 |
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Keywords
- subjective cognitive complaints
- subjective memory complaints
- dementia
- Alzheimer disease
- mild cognitive impairment
Cite this
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From Subjective Cognitive Complaints to Dementia : Who is at Risk?: A Systematic Review. / Sousa, Marcelo Duarte Dias Mendonça de; Alves, Luísa; Bugalho, Paulo.
In: American journal of Alzheimer's disease and other dementias, Vol. 31, No. 2, 03.2016, p. 105-14.Research output: Contribution to journal › Article
TY - JOUR
T1 - From Subjective Cognitive Complaints to Dementia
T2 - Who is at Risk?: A Systematic Review
AU - Sousa, Marcelo Duarte Dias Mendonça de
AU - Alves, Luísa
AU - Bugalho, Paulo
N1 - WOS:000374655600001 ID PubMed: 26142292
PY - 2016/3
Y1 - 2016/3
N2 - Subjective cognitive complaints (SCCs) are frequent in the elderly population. The majority of individuals with subjective complaints never progress to significant cognitive decline, but some of them have a higher risk of progression to objective cognitive impairment than persons with no cognitive concerns. We performed a systematic review of community-based studies that focused on the progression risk associated with SCC and on the complainers’ characteristics associated with progression. Seventeen studies were included. As a group, SCCs are associated with a significantly higher risk of progression to dementia. Worried complainers, persons who refer an impact of their complaints on activities of daily living, and those whose complaints are also noticed by an informant have the highest risk of progression. Taking into account the fluctuating course of SCC and their frequent reversion, care should be taken to not overvaluate them. Further studies are necessary to better define risk features.
AB - Subjective cognitive complaints (SCCs) are frequent in the elderly population. The majority of individuals with subjective complaints never progress to significant cognitive decline, but some of them have a higher risk of progression to objective cognitive impairment than persons with no cognitive concerns. We performed a systematic review of community-based studies that focused on the progression risk associated with SCC and on the complainers’ characteristics associated with progression. Seventeen studies were included. As a group, SCCs are associated with a significantly higher risk of progression to dementia. Worried complainers, persons who refer an impact of their complaints on activities of daily living, and those whose complaints are also noticed by an informant have the highest risk of progression. Taking into account the fluctuating course of SCC and their frequent reversion, care should be taken to not overvaluate them. Further studies are necessary to better define risk features.
KW - subjective cognitive complaints
KW - subjective memory complaints
KW - dementia
KW - Alzheimer disease
KW - mild cognitive impairment
U2 - 10.1177/1533317515592331
DO - 10.1177/1533317515592331
M3 - Article
VL - 31
SP - 105
EP - 114
JO - American journal of Alzheimer's disease and other dementias
JF - American journal of Alzheimer's disease and other dementias
SN - 1533-3175
IS - 2
ER -