Food Allergy and Anaphylaxis in Infants and Preschool-Age Children

Research output: Contribution to journalArticle

Abstract

Food allergy (FA) prevalence data in infants and preschool-age children are sparse, and proposed risk factors lack confirmation. In this study, 19 children's day care centers (DCC) from 2 main Portuguese cities were selected after stratification and cluster analysis. An ISAAC's (International Study of Asthma and Allergies in Childhood) derived health questionnaire was applied to a sample of children attending DCCs. Outcomes were FA parental report and anaphylaxis. Logistic regression was used to explore potential risk factors for reported FA. From the 2228 distributed questionnaires, 1217 were included in the analysis (54.6\%). Children's median age was 3.5 years, and 10.8\% were described as ever having had FA. Current FA was reported in 5.7\%. Three (0.2\%) reports compatible with anaphylaxis were identified. Reported parental history of FA, personal history of atopic dermatitis, and preterm birth increased the odds for reported current FA. A high prevalence of parental-perceived FA in preschool-age children was identified. Risk factor identification may enhance better prevention.
Original languageEnglish
Pages (from-to)652-657
Number of pages6
JournalClinical Pediatrics
Volume53
Issue number7
DOIs
Publication statusPublished - 2014

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Food Hypersensitivity
Anaphylaxis
Preschool Children
Child Day Care Centers
Premature Birth
Atopic Dermatitis
Cluster Analysis
Hypersensitivity
Asthma
Logistic Models
Health

Keywords

  • diagnosis
  • childhood
  • epidemiology
  • life
  • management
  • hypersensitivity
  • prevalence
  • united-states
  • intestinal permeability
  • 1st 3 years

Cite this

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title = "Food Allergy and Anaphylaxis in Infants and Preschool-Age Children",
abstract = "Food allergy (FA) prevalence data in infants and preschool-age children are sparse, and proposed risk factors lack confirmation. In this study, 19 children's day care centers (DCC) from 2 main Portuguese cities were selected after stratification and cluster analysis. An ISAAC's (International Study of Asthma and Allergies in Childhood) derived health questionnaire was applied to a sample of children attending DCCs. Outcomes were FA parental report and anaphylaxis. Logistic regression was used to explore potential risk factors for reported FA. From the 2228 distributed questionnaires, 1217 were included in the analysis (54.6\{\%}). Children's median age was 3.5 years, and 10.8\{\%} were described as ever having had FA. Current FA was reported in 5.7\{\%}. Three (0.2\{\%}) reports compatible with anaphylaxis were identified. Reported parental history of FA, personal history of atopic dermatitis, and preterm birth increased the odds for reported current FA. A high prevalence of parental-perceived FA in preschool-age children was identified. Risk factor identification may enhance better prevention.",
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author = "J Gaspar-Marques and P Carreiro-Martins and AL Papoila and I Caires and C Pedro and J Ara{\'u}jo-Martins and Daniel Virella and J Rosado-Pinto and P Leiria-Pinto and N Neuparth",
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T1 - Food Allergy and Anaphylaxis in Infants and Preschool-Age Children

AU - Gaspar-Marques, J

AU - Carreiro-Martins, P

AU - Papoila, AL

AU - Caires, I

AU - Pedro, C

AU - Araújo-Martins, J

AU - Virella, Daniel

AU - Rosado-Pinto, J

AU - Leiria-Pinto, P

AU - Neuparth, N

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AB - Food allergy (FA) prevalence data in infants and preschool-age children are sparse, and proposed risk factors lack confirmation. In this study, 19 children's day care centers (DCC) from 2 main Portuguese cities were selected after stratification and cluster analysis. An ISAAC's (International Study of Asthma and Allergies in Childhood) derived health questionnaire was applied to a sample of children attending DCCs. Outcomes were FA parental report and anaphylaxis. Logistic regression was used to explore potential risk factors for reported FA. From the 2228 distributed questionnaires, 1217 were included in the analysis (54.6\%). Children's median age was 3.5 years, and 10.8\% were described as ever having had FA. Current FA was reported in 5.7\%. Three (0.2\%) reports compatible with anaphylaxis were identified. Reported parental history of FA, personal history of atopic dermatitis, and preterm birth increased the odds for reported current FA. A high prevalence of parental-perceived FA in preschool-age children was identified. Risk factor identification may enhance better prevention.

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