Fibrodysplasia ossificans progressiva: Report of two cases

J. E. Fonseca, Jaime Branco, J. Reis, T. Evangelista, V. Tavares, A. Rodrigues Gomes, M. Viana Queiroz

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Fibrodysplasia Ossificans Progressiva (FOP) is a rare hereditary connective tissue disease, genetically inherited as an autosomal dominant trait with complete penetrance but variable expressivity. Onset is typically in childhood and progressive involvement of the spine and proximal extremities leads to immobility and articular dysfunction. We present two cases with the typical features of FOP and a review of the pathogenesis, clinical manifestations and treatment options of this rare disease.

Original languageEnglish
Pages (from-to)749-752
Number of pages4
JournalClinical and Experimental Rheumatology
Volume18
Issue number6
Publication statusPublished - 2000

Keywords

  • Ectopic ossification
  • Etidronate
  • Fibrodysplasia ossificans progressiva
  • Surgery

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