FELASA-AALAS Recommendations for Monitoring and Reporting of Laboratory Fish Diseases and Health Status, with an Emphasis on Zebrafish (Danio Rerio)

Jean Philippe Mocho, Chereen Collymore, Susan C. Farmer, Emmanuel Leguay, Katrina N. Murray, Nuno Pereira

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

The exchange of fish for research may expose an aquatic laboratory to pathogen contamination as incoming fish can introduce bacteria, fungi, parasites, and viruses capable of affecting both experimental results and fish and personnel health and welfare. To develop risk mitigation strategies, FELASA and AALAS established a joint working group to recommend good practices for health monitoring of laboratory fish. The recommendations address all fish species used for research, with a particular focus on zebrafish (Danio rerio). First, the background of the working group and key definitions are provided. Next, fish diseases of high impact are described. Third, recommendations are made for health monitoring of laboratory fishes. The recommendations emphasize the importance of daily observation of the fish and strategies to determine fish colony health status. Finally, report templates are proposed for historical screening data and aquatic facility description to facilitate biohazard risk assessment when exchanging fish.

Original languageEnglish
Pages (from-to)127-148
Number of pages22
JournalComparative medicine
Volume72
Issue number3
DOIs
Publication statusPublished - 1 Jun 2022

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