Exploring membrane respiratory chains

Bruno C. Marreiros, Filipa Calisto, Paulo J. Castro, Afonso M. Duarte, Filipa V. Sena, Andreia F. Silva, Filipe M. Sousa, Miguel Teixeira, Ana Patrícia Refojo, Manuela Alexandra Pereira

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Acquisition of energy is central to life. In addition to the synthesis of ATP, organisms need energy for the establishment and maintenance of a transmembrane difference in electrochemical potential, in order to import and export metabolites or to their motility. The membrane potential is established by a variety of membrane bound respiratory complexes. In this work we explored the diversity of membrane respiratory chains and the presence of the different enzyme complexes in the several phyla of life. We performed taxonomic profiles of the several membrane bound respiratory proteins and complexes evaluating the presence of their respective coding genes in all species deposited in KEGG database. We evaluated 26 quinone reductases, 5 quinol:electron carriers oxidoreductases and 18 terminal electron acceptor reductases. We further included in the analyses enzymes performing redox or decarboxylation driven ion translocation, ATP synthase and transhydrogenase and we also investigated the electron carriers that perform functional connection between the membrane complexes, quinones or soluble proteins. Our results bring a novel, broad and integrated perspective of membrane bound respiratory complexes and thus of the several energetic metabolisms of living systems. This article is part of a Special Issue entitled ‘EBEC 2016: 19th European Bioenergetics Conference, Riva del Garda, Italy, July 2–6, 2016’, edited by Prof. Paolo Bernardi.

Original languageEnglish
Pages (from-to)1039-1067
Number of pages29
JournalBiochimica Et Biophysica Acta-Bioenergetics
Volume1857
Issue number8
DOIs
Publication statusPublished - 1 Aug 2016

Fingerprint

Electron Transport
Membranes
Electrons
Quinone Reductases
Oxidoreductases
Adenosine Triphosphate
Hydroquinones
Quinones
Decarboxylation
Enzymes
Membrane Potentials
Energy Metabolism
Italy
Oxidation-Reduction
Metabolites
Proteins
Metabolism
Maintenance
Databases
Ions

Keywords

  • Anaerobe
  • Ion transport
  • Oxygen
  • Quinone
  • Respiration
  • Taxonomic profile

Cite this

Marreiros, Bruno C. ; Calisto, Filipa ; Castro, Paulo J. ; Duarte, Afonso M. ; Sena, Filipa V. ; Silva, Andreia F. ; Sousa, Filipe M. ; Teixeira, Miguel ; Refojo, Ana Patrícia ; Pereira, Manuela Alexandra. / Exploring membrane respiratory chains. In: Biochimica Et Biophysica Acta-Bioenergetics. 2016 ; Vol. 1857, No. 8. pp. 1039-1067.
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Exploring membrane respiratory chains. / Marreiros, Bruno C.; Calisto, Filipa; Castro, Paulo J.; Duarte, Afonso M.; Sena, Filipa V.; Silva, Andreia F.; Sousa, Filipe M.; Teixeira, Miguel; Refojo, Ana Patrícia; Pereira, Manuela Alexandra.

In: Biochimica Et Biophysica Acta-Bioenergetics, Vol. 1857, No. 8, 01.08.2016, p. 1039-1067.

Research output: Contribution to journalArticle

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T1 - Exploring membrane respiratory chains

AU - Marreiros, Bruno C.

AU - Calisto, Filipa

AU - Castro, Paulo J.

AU - Duarte, Afonso M.

AU - Sena, Filipa V.

AU - Silva, Andreia F.

AU - Sousa, Filipe M.

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AU - Pereira, Manuela Alexandra

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Marreiros BC, Calisto F, Castro PJ, Duarte AM, Sena FV, Silva AF et al. Exploring membrane respiratory chains. Biochimica Et Biophysica Acta-Bioenergetics. 2016 Aug 1;1857(8):1039-1067. https://doi.org/10.1016/j.bbabio.2016.03.028