Ethylmalonic encephalopathy ETHE1 R163W/R163Q mutations alter protein stability and redox properties of the iron centre

Medicine & Life Sciences

• Ethylmalonic encephalopathy 100%
• Protein Stability 59%
• Oxidation-Reduction 48%
• Iron 42%
• Mutation 28%
• Sulfides 19%
• Proteins 18%
• ferrous sulfate 10%
• Benchmarking 7%
• Point Mutation 7%
• Rare Diseases 7%
• Zinc 6%
• Catalytic Domain 6%
• Hot Temperature 5%

Agriculture & Biology

• encephalopathy 72%
• iron 37%
• mutation 34%
• proteins 17%
• sulfides 15%
• point mutation 7%
• protein structure 7%
• catalytic activity 6%
• active sites 6%
• thermal stability 6%
• chemistry 6%
• zinc 5%
• oxidation 5%
• toxicity 4%
• cells 2%

Chemistry

• Mutation 42%
• Protein Tertiary Structure 26%
• Protein 20%
• Sulfide 15%
• Iron Protein 15%
• Reduction Potential 10%
• Protein Structure 9%
• Thermal Stability 6%
• Chemistry 5%
• Oxidation Reaction 4%
• Reaction Yield 4%