Ethylenediamine-N,N'-diglutaric acid (EDDG) as a promising biodegradable chelator: quantification, complexation and biodegradation

Ana B. Lanham, Mónica Carvalheira, Alexandre Mourão Rodrigues, Vitor Vale Cardoso, Maria João Benoliel, Teresa Barros Maria, Maria João Morgado, Helena M.V.M. Soares, Paulo Costa Lemos, Maria A. M. Reis

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[S,S]-ethylenediamine-N,N'-diglutaric acid (EDDG) has been gaining interest in the industrial sector as a promising chelator. In this study, the effective metal complexing capacity of EDDG over a wide pH range was modelled and its biodegradability assessed. Results showed that EDDG could effectively bind to several metallic ions in a wide pH range and was completely biodegraded after approximately 15 days by un-acclimatized sludge. To confirm its biodegradability, an accurate quantification method based on the combination of liquid chromatography and tandem quadrupole mass spectrometry (LC-MS/MS) was developed. Good linearity of the detector response was found for EDDG at concentrations ranging from 0,15 to 1,2 mg/L.

Original languageEnglish
Pages (from-to)553-559
Number of pages7
JournalJournal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering
Issue number6
Publication statusPublished - 1 Jan 2011



  • Biodegradable
  • Chemical analysis
  • Environmental chemistry
  • Waste water

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