Environmental distribution of Cryptococcus neoformans and C. Gattii around the Mediterranean basin

Massimo Cogliati; Roberta D'Amicis; Alberto Zani; Maria Teresa Montagna; Giuseppina Caggiano; Osvalda De Giglio; Stella Balbino; Antonella De Donno; Francesca Serio; Serdar Susever; Cagri Ergin; Aristea Velegraki; Mohamed S. Ellabib; Simona Nardoni; Cristina Macci; Salvatore Oliveri; Laura Trovato; Ludovico Dipineto; Volker Rickerts; Ilka McCormick-Smith; Sevim Akcaglar; Okan Tore; Emilija Mlinaric-Missoni; Sebastien Bertout; Michele Mallié; Maria da Luz Martins; Ana C F Vencà; Maria L. Vieira; Ana C. Sampaio; Cheila Pereira; Giuseppe Criseo; Orazio Romeo; Stéphane Ranque; Mohammed H Y Al-Yasiri; Meltem Kaya; Nilgun Cerikcioglu; Anna Marchese; Luigi Vezzulli; Macit Ilkit; Marie Desnos-Ollivier; Vincenzo Pasquale; Maya Korem; Itzhack Polacheck; Antonio Scopa; Wieland Meyer; Kennio Ferreira-Paim; Ferry Hagen; Bart Theelen; Teun Boekhout; Shawn R. Lockhart; Kathrin Tintelnot; Anna Maria Tortorano; Françoise Dromer; Ashok Varma; Kyung J. Kwon-Chung; João Inácio; Beatriz Alonso; Maria F. Colom

doi:10.1093/femsyr/fow045

Environmental distribution of Cryptococcus neoformans and C. Gattii around the Mediterranean basin

Massimo Cogliati, Roberta D'Amicis, Alberto Zani, Maria Teresa Montagna, Giuseppina Caggiano, Osvalda De Giglio, Stella Balbino, Antonella De Donno, Francesca Serio, Serdar Susever, Cagri Ergin, Aristea Velegraki, Mohamed S. Ellabib, Simona Nardoni, Cristina Macci, Salvatore Oliveri, Laura Trovato, Ludovico Dipineto, Volker Rickerts, Ilka McCormick-SmithSevim Akcaglar, Okan Tore, Emilija Mlinaric-Missoni, Sebastien Bertout, Michele Mallié, Maria da Luz Martins, Ana C F Vencà, Maria L. Vieira, Ana C. Sampaio, Cheila Pereira, Giuseppe Criseo, Orazio Romeo, Stéphane Ranque, Mohammed H Y Al-Yasiri, Meltem Kaya, Nilgun Cerikcioglu, Anna Marchese, Luigi Vezzulli, Macit Ilkit, Marie Desnos-Ollivier, Vincenzo Pasquale, Maya Korem, Itzhack Polacheck, Antonio Scopa, Wieland Meyer, Kennio Ferreira-Paim, Ferry Hagen, Bart Theelen, Teun Boekhout, Shawn R. Lockhart, Kathrin Tintelnot, Anna Maria Tortorano, Françoise Dromer, Ashok Varma, Kyung J. Kwon-Chung, João Inácio, Beatriz Alonso, Maria F. Colom

Instituto de Higiene e Medicina Tropical (IHMT)

Research output: Contribution to journal › Article › peer-review

57 Citations (Scopus)

Abstract

In order to elucidate the distribution of Cryptococcus neoformans and C. gattii in the Mediterranean basin, an extensive environmental survey was carried out during 2012-2015. A total of 302 sites located in 12 countries were sampled, 6436 samples from 3765 trees were collected and 5% of trees were found to be colonized by cryptococcal yeasts. Cryptococcus neoformans was isolated from 177 trees and C. gattii from 13. Cryptococcus neoformans colonized 27% of Ceratonia, 10% of Olea, Platanus and Prunus trees and a lower percentage of other tree genera. The 13 C. gattii isolates were collected from five Eucalyptus, four Ceratonia, two Pinus and two Olea trees. Cryptococcus neoformans was distributed all around the Mediterranean basin, whereas C. gattii was isolated in Greece, Southern Italy and Spain, in agreement with previous findings from both clinical and environmental sources. Among C. neoformans isolates, VNI was the prevalent molecular type but VNII, VNIV and VNIII hybrid strains were also isolated. With the exception of a single VGIV isolate, all C. gattii isolates were VGI. The results confirmed the presence of both Cryptococcus species in the Mediterranean environment, and showed that both carob and olive trees represent an important niche for these yeasts.

Original language	English
Pages (from-to)	1-12
Number of pages	12
Journal	FEMS Yeast Research
Volume	16
Issue number	4
DOIs	https://doi.org/10.1093/femsyr/fow045
Publication status	Published - 1 Jun 2016

Keywords

C. gattii
C. neoformans
Cryptococcus
Environment
Epidemiology
Europe
Molecular typing

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/femsyr/fow045

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Cogliati, M., D'Amicis, R., Zani, A., Montagna, M. T., Caggiano, G., De Giglio, O., Balbino, S., De Donno, A., Serio, F., Susever, S., Ergin, C., Velegraki, A., Ellabib, M. S., Nardoni, S., Macci, C., Oliveri, S., Trovato, L., Dipineto, L., Rickerts, V., ... Colom, M. F. (2016). Environmental distribution of Cryptococcus neoformans and C. Gattii around the Mediterranean basin. FEMS Yeast Research, 16(4), 1-12. https://doi.org/10.1093/femsyr/fow045

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title = "Environmental distribution of Cryptococcus neoformans and C. Gattii around the Mediterranean basin",

abstract = "In order to elucidate the distribution of Cryptococcus neoformans and C. gattii in the Mediterranean basin, an extensive environmental survey was carried out during 2012-2015. A total of 302 sites located in 12 countries were sampled, 6436 samples from 3765 trees were collected and 5% of trees were found to be colonized by cryptococcal yeasts. Cryptococcus neoformans was isolated from 177 trees and C. gattii from 13. Cryptococcus neoformans colonized 27% of Ceratonia, 10% of Olea, Platanus and Prunus trees and a lower percentage of other tree genera. The 13 C. gattii isolates were collected from five Eucalyptus, four Ceratonia, two Pinus and two Olea trees. Cryptococcus neoformans was distributed all around the Mediterranean basin, whereas C. gattii was isolated in Greece, Southern Italy and Spain, in agreement with previous findings from both clinical and environmental sources. Among C. neoformans isolates, VNI was the prevalent molecular type but VNII, VNIV and VNIII hybrid strains were also isolated. With the exception of a single VGIV isolate, all C. gattii isolates were VGI. The results confirmed the presence of both Cryptococcus species in the Mediterranean environment, and showed that both carob and olive trees represent an important niche for these yeasts.",

keywords = "C. gattii, C. neoformans, Cryptococcus, Environment, Epidemiology, Europe, Molecular typing",

author = "Massimo Cogliati and Roberta D'Amicis and Alberto Zani and Montagna, {Maria Teresa} and Giuseppina Caggiano and {De Giglio}, Osvalda and Stella Balbino and {De Donno}, Antonella and Francesca Serio and Serdar Susever and Cagri Ergin and Aristea Velegraki and Ellabib, {Mohamed S.} and Simona Nardoni and Cristina Macci and Salvatore Oliveri and Laura Trovato and Ludovico Dipineto and Volker Rickerts and Ilka McCormick-Smith and Sevim Akcaglar and Okan Tore and Emilija Mlinaric-Missoni and Sebastien Bertout and Michele Malli{\'e} and {da Luz Martins}, Maria and Venc{\`a}, {Ana C F} and Vieira, {Maria L.} and Sampaio, {Ana C.} and Cheila Pereira and Giuseppe Criseo and Orazio Romeo and St{\'e}phane Ranque and Al-Yasiri, {Mohammed H Y} and Meltem Kaya and Nilgun Cerikcioglu and Anna Marchese and Luigi Vezzulli and Macit Ilkit and Marie Desnos-Ollivier and Vincenzo Pasquale and Maya Korem and Itzhack Polacheck and Antonio Scopa and Wieland Meyer and Kennio Ferreira-Paim and Ferry Hagen and Bart Theelen and Teun Boekhout and Lockhart, {Shawn R.} and Kathrin Tintelnot and Tortorano, {Anna Maria} and Fran{\c c}oise Dromer and Ashok Varma and Kwon-Chung, {Kyung J.} and Jo{\~a}o In{\'a}cio and Beatriz Alonso and Colom, {Maria F.}",

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doi = "10.1093/femsyr/fow045",

language = "English",

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Cogliati, M, D'Amicis, R, Zani, A, Montagna, MT, Caggiano, G, De Giglio, O, Balbino, S, De Donno, A, Serio, F, Susever, S, Ergin, C, Velegraki, A, Ellabib, MS, Nardoni, S, Macci, C, Oliveri, S, Trovato, L, Dipineto, L, Rickerts, V, McCormick-Smith, I, Akcaglar, S, Tore, O, Mlinaric-Missoni, E, Bertout, S, Mallié, M, da Luz Martins, M, Vencà, ACF, Vieira, ML, Sampaio, AC, Pereira, C, Criseo, G, Romeo, O, Ranque, S, Al-Yasiri, MHY, Kaya, M, Cerikcioglu, N, Marchese, A, Vezzulli, L, Ilkit, M, Desnos-Ollivier, M, Pasquale, V, Korem, M, Polacheck, I, Scopa, A, Meyer, W, Ferreira-Paim, K, Hagen, F, Theelen, B, Boekhout, T, Lockhart, SR, Tintelnot, K, Tortorano, AM, Dromer, F, Varma, A, Kwon-Chung, KJ, Inácio, J, Alonso, B & Colom, MF 2016, 'Environmental distribution of Cryptococcus neoformans and C. Gattii around the Mediterranean basin', FEMS Yeast Research, vol. 16, no. 4, pp. 1-12. https://doi.org/10.1093/femsyr/fow045

TY - JOUR

T1 - Environmental distribution of Cryptococcus neoformans and C. Gattii around the Mediterranean basin

AU - Cogliati, Massimo

AU - D'Amicis, Roberta

AU - Zani, Alberto

AU - Montagna, Maria Teresa

AU - Caggiano, Giuseppina

AU - De Giglio, Osvalda

AU - Balbino, Stella

AU - De Donno, Antonella

AU - Serio, Francesca

AU - Susever, Serdar

AU - Ergin, Cagri

AU - Velegraki, Aristea

AU - Ellabib, Mohamed S.

AU - Nardoni, Simona

AU - Macci, Cristina

AU - Oliveri, Salvatore

AU - Trovato, Laura

AU - Dipineto, Ludovico

AU - Rickerts, Volker

AU - McCormick-Smith, Ilka

AU - Akcaglar, Sevim

AU - Tore, Okan

AU - Mlinaric-Missoni, Emilija

AU - Bertout, Sebastien

AU - Mallié, Michele

AU - da Luz Martins, Maria

AU - Vencà, Ana C F

AU - Vieira, Maria L.

AU - Sampaio, Ana C.

AU - Pereira, Cheila

AU - Criseo, Giuseppe

AU - Romeo, Orazio

AU - Ranque, Stéphane

AU - Al-Yasiri, Mohammed H Y

AU - Kaya, Meltem

AU - Cerikcioglu, Nilgun

AU - Marchese, Anna

AU - Vezzulli, Luigi

AU - Ilkit, Macit

AU - Desnos-Ollivier, Marie

AU - Pasquale, Vincenzo

AU - Korem, Maya

AU - Polacheck, Itzhack

AU - Scopa, Antonio

AU - Meyer, Wieland

AU - Ferreira-Paim, Kennio

AU - Hagen, Ferry

AU - Theelen, Bart

AU - Boekhout, Teun

AU - Lockhart, Shawn R.

AU - Tintelnot, Kathrin

AU - Tortorano, Anna Maria

AU - Dromer, Françoise

AU - Varma, Ashok

AU - Kwon-Chung, Kyung J.

AU - Inácio, João

AU - Alonso, Beatriz

AU - Colom, Maria F.

PY - 2016/6/1

Y1 - 2016/6/1

N2 - In order to elucidate the distribution of Cryptococcus neoformans and C. gattii in the Mediterranean basin, an extensive environmental survey was carried out during 2012-2015. A total of 302 sites located in 12 countries were sampled, 6436 samples from 3765 trees were collected and 5% of trees were found to be colonized by cryptococcal yeasts. Cryptococcus neoformans was isolated from 177 trees and C. gattii from 13. Cryptococcus neoformans colonized 27% of Ceratonia, 10% of Olea, Platanus and Prunus trees and a lower percentage of other tree genera. The 13 C. gattii isolates were collected from five Eucalyptus, four Ceratonia, two Pinus and two Olea trees. Cryptococcus neoformans was distributed all around the Mediterranean basin, whereas C. gattii was isolated in Greece, Southern Italy and Spain, in agreement with previous findings from both clinical and environmental sources. Among C. neoformans isolates, VNI was the prevalent molecular type but VNII, VNIV and VNIII hybrid strains were also isolated. With the exception of a single VGIV isolate, all C. gattii isolates were VGI. The results confirmed the presence of both Cryptococcus species in the Mediterranean environment, and showed that both carob and olive trees represent an important niche for these yeasts.

AB - In order to elucidate the distribution of Cryptococcus neoformans and C. gattii in the Mediterranean basin, an extensive environmental survey was carried out during 2012-2015. A total of 302 sites located in 12 countries were sampled, 6436 samples from 3765 trees were collected and 5% of trees were found to be colonized by cryptococcal yeasts. Cryptococcus neoformans was isolated from 177 trees and C. gattii from 13. Cryptococcus neoformans colonized 27% of Ceratonia, 10% of Olea, Platanus and Prunus trees and a lower percentage of other tree genera. The 13 C. gattii isolates were collected from five Eucalyptus, four Ceratonia, two Pinus and two Olea trees. Cryptococcus neoformans was distributed all around the Mediterranean basin, whereas C. gattii was isolated in Greece, Southern Italy and Spain, in agreement with previous findings from both clinical and environmental sources. Among C. neoformans isolates, VNI was the prevalent molecular type but VNII, VNIV and VNIII hybrid strains were also isolated. With the exception of a single VGIV isolate, all C. gattii isolates were VGI. The results confirmed the presence of both Cryptococcus species in the Mediterranean environment, and showed that both carob and olive trees represent an important niche for these yeasts.

KW - C. gattii

KW - C. neoformans

KW - Cryptococcus

KW - Environment

KW - Epidemiology

KW - Europe

KW - Molecular typing

UR - http://www.scopus.com/inward/record.url?scp=84973092398&partnerID=8YFLogxK

U2 - 10.1093/femsyr/fow045

DO - 10.1093/femsyr/fow045

M3 - Article

AN - SCOPUS:84973092398

SN - 1567-1356

VL - 16

SP - 1

EP - 12

JO - FEMS Yeast Research

JF - FEMS Yeast Research

IS - 4

ER -

Environmental distribution of Cryptococcus neoformans and C. Gattii around the Mediterranean basin

Abstract

Keywords

UN SDGs

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