@article{748a07be902445a8aa3512facdccd0a7,
title = "Electronic control of drug release from gauze or cellulose acetate fibres for dermal applications",
abstract = "Electronic controlled drug release from fibres was studied using ibuprofen as a model drug, one of the most popular analgesics, to impregnate gauze and cellulose acetate (CA) membranes. Conductivity in the range of 1-10 mS cm−1was obtained in polypyrrole (Ppy) functionalised gauze and CA fibres, providing voltage-controlled drug release in a system consisting of Ppy/Ibuprofen/Ppy membranes and an Ag electrode. SEM images evidenced the Ppy adhesion to fibres and Micro Raman spectra proved drug incorporation and release. A small wound adhesive built with these membranes retains ibuprofen at 1.5 V and quickly releases it when −0.5 V is applied.",
author = "Baptista, {Ana Catarina} and Miguel Brito and Marques, {Ana Cl{\'a}udia} and Isabel Ferreira",
note = "info:eu-repo/grantAgreement/EC/H2020/647596/EU# info:eu-repo/grantAgreement/EC/H2020/645241/EU# This work was mainly funded FEDER funds through the COMPETE 2020 Program and National Funds through FCT - Portuguese Foundation for Science and Technology under the projects UID/CTM/50025/2019, UIDB/50025/2020-2023 and partially by ERC-CoG-2014, ERC-POC-2019, CAPSEL, 855018. The authors would like to thank the use of the electrospinning apparatus at the Biomaterials Laboratory from Soft and Bio-functional Materials Group (CENIMAT/I3N).",
year = "2021",
month = apr,
day = "28",
doi = "10.1039/d1tb00249j",
language = "English",
volume = "9",
pages = "3515--3522",
journal = "Journal of Materials Chemistry B",
issn = "2050-750X",
publisher = "RSC - Royal Society of Chemistry",
number = "16",
}