Both hydroxyapatite (HA) and chitosan (CS) are biomaterials with known medical applications. Synthetic hydroxyapatite [HA, Ca10(PO4)6(OH)2] is a bioceramic widely used in hard tissue regeneration. Chitosan is a polysaccharide obtained from chitin present in exoskeleton of crustaceans and in funghi. This biopolymer has a great potential for biomedical applications in wound dressing because it is biodegradable, hypoallergenic, an antibacterial agent and can clot blood . All these properties also make CS a suitable material to add to HA used in orthopedic and dental surgery to help improve healing and osseointegration. Because of the piezoelectric character of bone  electrical stress can accelerate remodeling and regeneration of bone. In the 1990’s Yamasihita and coworkers  started using thermal polarization of HA to increase its bioactivity. In this work a composite of chitosan n and hydroxypatite was produced and electrically polarized by thermal polarization. Thermally stimulated discharge currents technique (TSDC) was used to study resulting polarization.
|Place of Publication||Baltimore, USA|
|Publication status||Published - 1 Jan 2014|