Effects of synthetic salmon calcitonin therapy in children with osteogenesis imperfecta

I Rebelo; Luis Pereira-da-Silva; J C Blanco; Maria Elisa Monteiro; N C Ferreira

doi:10.1177/030006058901700415

Effects of synthetic salmon calcitonin therapy in children with osteogenesis imperfecta

I Rebelo, Luis Pereira-da-Silva, J C Blanco, Maria Elisa Monteiro, N C Ferreira

NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)

Research output: Contribution to journal › Article

6 Citations (Scopus)

Abstract

A total of four children with osteogenesis imperfecta, three with type I and one with type III forms of the disease, were treated with synthetic salmon calcitonin for 18-24 months. The annual fracture rate was decreased during calcitonin therapy compared with the period preceding it. No patient presented a marked inflexion in linear growth and a transient improvement was even noticed in two cases.

Original language	English
Pages (from-to)	401-5
Number of pages	5
Journal	Journal of molecular medicine (Berlin, Germany)
Volume	17
Issue number	4
DOIs	https://doi.org/10.1177/030006058901700415
Publication status	Published - Jul 1989

Keywords

Age Determination by Skeleton
Body Height
Bone Development
Calcitonin
Child
Child, Preschool
Female
Fractures, Bone
Humans
Male
Osteogenesis Imperfecta
Journal Article

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title = "Effects of synthetic salmon calcitonin therapy in children with osteogenesis imperfecta",

abstract = "A total of four children with osteogenesis imperfecta, three with type I and one with type III forms of the disease, were treated with synthetic salmon calcitonin for 18-24 months. The annual fracture rate was decreased during calcitonin therapy compared with the period preceding it. No patient presented a marked inflexion in linear growth and a transient improvement was even noticed in two cases.",

keywords = "Age Determination by Skeleton, Body Height, Bone Development, Calcitonin, Child, Child, Preschool, Female, Fractures, Bone, Humans, Male, Osteogenesis Imperfecta, Journal Article",

author = "I Rebelo and Luis Pereira-da-Silva and Blanco, {J C} and Monteiro, {Maria Elisa} and Ferreira, {N C}",

year = "1989",

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language = "English",

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T1 - Effects of synthetic salmon calcitonin therapy in children with osteogenesis imperfecta

AU - Rebelo, I

AU - Pereira-da-Silva, Luis

AU - Blanco, J C

AU - Monteiro, Maria Elisa

AU - Ferreira, N C

PY - 1989/7

Y1 - 1989/7

N2 - A total of four children with osteogenesis imperfecta, three with type I and one with type III forms of the disease, were treated with synthetic salmon calcitonin for 18-24 months. The annual fracture rate was decreased during calcitonin therapy compared with the period preceding it. No patient presented a marked inflexion in linear growth and a transient improvement was even noticed in two cases.

AB - A total of four children with osteogenesis imperfecta, three with type I and one with type III forms of the disease, were treated with synthetic salmon calcitonin for 18-24 months. The annual fracture rate was decreased during calcitonin therapy compared with the period preceding it. No patient presented a marked inflexion in linear growth and a transient improvement was even noticed in two cases.

KW - Age Determination by Skeleton

KW - Body Height

KW - Bone Development

KW - Calcitonin

KW - Child

KW - Child, Preschool

KW - Female

KW - Fractures, Bone

KW - Humans

KW - Male

KW - Osteogenesis Imperfecta

KW - Journal Article

U2 - 10.1177/030006058901700415

DO - 10.1177/030006058901700415

M3 - Article

C2 - 2792559

VL - 17

SP - 401

EP - 405

JO - Journal of molecular medicine (Berlin, Germany)

JF - Journal of molecular medicine (Berlin, Germany)

SN - 0946-2716

IS - 4

ER -