Abstract
A total of four children with osteogenesis imperfecta, three with type I and one with type III forms of the disease, were treated with synthetic salmon calcitonin for 18-24 months. The annual fracture rate was decreased during calcitonin therapy compared with the period preceding it. No patient presented a marked inflexion in linear growth and a transient improvement was even noticed in two cases.
| Original language | English |
|---|---|
| Pages (from-to) | 401-5 |
| Number of pages | 5 |
| Journal | Journal of molecular medicine (Berlin, Germany) |
| Volume | 17 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Jul 1989 |
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Keywords
- Age Determination by Skeleton
- Body Height
- Bone Development
- Calcitonin
- Child
- Child, Preschool
- Female
- Fractures, Bone
- Humans
- Male
- Osteogenesis Imperfecta
- Journal Article
Cite this
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Effects of synthetic salmon calcitonin therapy in children with osteogenesis imperfecta. / Rebelo, I; Pereira-da-Silva, Luis; Blanco, J C; Monteiro, Maria Elisa; Ferreira, N C.
In: Journal of molecular medicine (Berlin, Germany), Vol. 17, No. 4, 07.1989, p. 401-5.Research output: Contribution to journal › Article
TY - JOUR
T1 - Effects of synthetic salmon calcitonin therapy in children with osteogenesis imperfecta
AU - Rebelo, I
AU - Pereira-da-Silva, Luis
AU - Blanco, J C
AU - Monteiro, Maria Elisa
AU - Ferreira, N C
PY - 1989/7
Y1 - 1989/7
N2 - A total of four children with osteogenesis imperfecta, three with type I and one with type III forms of the disease, were treated with synthetic salmon calcitonin for 18-24 months. The annual fracture rate was decreased during calcitonin therapy compared with the period preceding it. No patient presented a marked inflexion in linear growth and a transient improvement was even noticed in two cases.
AB - A total of four children with osteogenesis imperfecta, three with type I and one with type III forms of the disease, were treated with synthetic salmon calcitonin for 18-24 months. The annual fracture rate was decreased during calcitonin therapy compared with the period preceding it. No patient presented a marked inflexion in linear growth and a transient improvement was even noticed in two cases.
KW - Age Determination by Skeleton
KW - Body Height
KW - Bone Development
KW - Calcitonin
KW - Child
KW - Child, Preschool
KW - Female
KW - Fractures, Bone
KW - Humans
KW - Male
KW - Osteogenesis Imperfecta
KW - Journal Article
U2 - 10.1177/030006058901700415
DO - 10.1177/030006058901700415
M3 - Article
VL - 17
SP - 401
EP - 405
JO - Journal of molecular medicine (Berlin, Germany)
JF - Journal of molecular medicine (Berlin, Germany)
SN - 0946-2716
IS - 4
ER -