Effects of Penicillium chrysogenum var. halophenolicum on kraft lignin

color stabilization and cytotoxicity evaluation

Marlene Remédios, Filomena A. Carvalho, Francisco J. Enguita, Carlos Cardoso, Ivo C. Martins, Nuno C. Santos, Ana Lúcia Leitão

Research output: Contribution to journalArticle

3 Citations (Scopus)
14 Downloads (Pure)

Abstract

Wood industries and agricultural crops generate an inexhaustible supply of by-products like lignin, which constitutes an environmental problem. Increasing efforts have been done to find new applications for lignin. One of them is as a food additive, but its chemical nature makes it sensitive to browning which constitutes a major drawback for this type of lignin application. In the present study we are documenting how color stabilization of a commercial kraft lignin was achieved after the treatment with Penicillium chrysogenum var. halophenolicum. In addition the fungal capacity to remove lignin is studied together with the effect of its treatment on cytotoxicity of lignin. P. chrysogenum var. halophenolicum was able to transform lignin, ensuring its color stability for more than 24 months. Dynamic light scattering and atomic force microscopy showed that the fungus contributed to homogenize particle size and hydrodynamic properties in lignin suspensions without increase the toxicity over HeLa cells and human primary fibroblasts. These findings suggest new uses for kraft lignin after P. chrysogenum var. halophenolicum treatment providing an effective approach for improve color stability.

Original languageEnglish
Article number102
Pages (from-to)1-10
Number of pages10
Journal3 Biotech
Volume6
Issue number1
DOIs
Publication statusPublished - Jun 2016

Fingerprint

Penicillium chrysogenum
Lignin
lignin
cytotoxicity
stabilization
Color
color
Agricultural Crops
Food Additives
Atomic Force Microscopy
Hydrodynamics
wood industry
Kraft lignin
evaluation
effect
HeLa Cells
Particle Size
atomic force microscopy
food additives
light scattering

Keywords

  • Color
  • Lignin removal
  • Penicillium chrysogenum var. halophenolicum
  • Toxicity
  • Transformation

Cite this

Remédios, Marlene ; Carvalho, Filomena A. ; Enguita, Francisco J. ; Cardoso, Carlos ; Martins, Ivo C. ; Santos, Nuno C. ; Leitão, Ana Lúcia. / Effects of Penicillium chrysogenum var. halophenolicum on kraft lignin : color stabilization and cytotoxicity evaluation. In: 3 Biotech. 2016 ; Vol. 6, No. 1. pp. 1-10.
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Effects of Penicillium chrysogenum var. halophenolicum on kraft lignin : color stabilization and cytotoxicity evaluation. / Remédios, Marlene; Carvalho, Filomena A.; Enguita, Francisco J.; Cardoso, Carlos; Martins, Ivo C.; Santos, Nuno C.; Leitão, Ana Lúcia.

In: 3 Biotech, Vol. 6, No. 1, 102, 06.2016, p. 1-10.

Research output: Contribution to journalArticle

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AU - Leitão, Ana Lúcia

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