TY - JOUR
T1 - Effect of extraction methodologies and solvent selection upon cynaropicrin extraction from Cynara cardunculus leaves
AU - Brás, Teresa
AU - Neves, Luísa A.
AU - Crespo, J. G.
AU - Duarte, Maria F.
N1 -
ALT20-03-0145-FEDER-000038
SFRH/BD/110969/2015
IF/00505/2014/CP1224/CT0004
UID/QUI/50006/2019
UID/AGR/00115/2019
Sem PDF conforme despacho.
PY - 2020/4/1
Y1 - 2020/4/1
N2 - Conventional extraction technologies to recover sesquiterpene lactones, relay on long extraction periods, with high temperatures, and use of organic solvents, often leading to degradation of target compounds. Within the present study, the effect of environmentally friendly, and economically viable methodologies, namely ultrasound assisted extraction, using biocompatible solvents, upon cynaropicrin, a sesquiterpene lactone found in Cynara cardunculus leaves was evaluated. Hansen solubility parameters, cynaropicrin extraction yield and energy consumption were evaluated. The ultrasound assisted extraction, using ethanol, showed to be the best cynaropicrin extraction methodology, leading to a reduction of 99% of extraction time (7 h to 5 min), a 30% increase of the cynaropicrin extraction yield (40.32–55.00 mg/g Dry Weight), and a 97% reduction of energy consumption (1.160–0.027 kWh/gcynaropicrin), compared to Soxhlet extraction. The results obtained from this study may be easily transposed to other sesquiterpene lactones extraction processes, with industrial relevance, as an alternative to conventional extraction methodologies.
AB - Conventional extraction technologies to recover sesquiterpene lactones, relay on long extraction periods, with high temperatures, and use of organic solvents, often leading to degradation of target compounds. Within the present study, the effect of environmentally friendly, and economically viable methodologies, namely ultrasound assisted extraction, using biocompatible solvents, upon cynaropicrin, a sesquiterpene lactone found in Cynara cardunculus leaves was evaluated. Hansen solubility parameters, cynaropicrin extraction yield and energy consumption were evaluated. The ultrasound assisted extraction, using ethanol, showed to be the best cynaropicrin extraction methodology, leading to a reduction of 99% of extraction time (7 h to 5 min), a 30% increase of the cynaropicrin extraction yield (40.32–55.00 mg/g Dry Weight), and a 97% reduction of energy consumption (1.160–0.027 kWh/gcynaropicrin), compared to Soxhlet extraction. The results obtained from this study may be easily transposed to other sesquiterpene lactones extraction processes, with industrial relevance, as an alternative to conventional extraction methodologies.
KW - Cynara cardunculus leaves extracts
KW - Cynaropicrin-guaianolide-type sesquiterpene lactone
KW - Hansen solubility parameters
KW - Non-conventional extraction methodologies
KW - Ultrasound assisted extraction
UR - http://www.scopus.com/inward/record.url?scp=85075373041&partnerID=8YFLogxK
U2 - 10.1016/j.seppur.2019.116283
DO - 10.1016/j.seppur.2019.116283
M3 - Article
AN - SCOPUS:85075373041
SN - 1383-5866
VL - 236
JO - Separation and Purification Technology
JF - Separation and Purification Technology
M1 - 116283
ER -
