TY - JOUR
T1 - Drug-induced accelerated nodulosis
T2 - review of the literature
AU - Palmeiro, Ana G.
AU - Lourenço, Maria H.
AU - Miroux-Catarino, Alexandre
AU - Crispim, Inês
AU - Branco, Jaime C.
AU - Viana, Isabel
PY - 2023/3
Y1 - 2023/3
N2 - Accelerated nodulosis, the rapid progression/extension of preexisting nodules, is a recognized complication of immunomodulatory therapy, occurring mostly in patients with rheumatoid arthritis treated with methotrexate. As of today, its physiopathology remains incompletely understood, and there are no standardized guidelines regarding its management. Here, we conduct a literature review of the reported cases of drug-induced accelerated nodulosis and add our case of a 79-year-old female with an atypical clinical presentation.
AB - Accelerated nodulosis, the rapid progression/extension of preexisting nodules, is a recognized complication of immunomodulatory therapy, occurring mostly in patients with rheumatoid arthritis treated with methotrexate. As of today, its physiopathology remains incompletely understood, and there are no standardized guidelines regarding its management. Here, we conduct a literature review of the reported cases of drug-induced accelerated nodulosis and add our case of a 79-year-old female with an atypical clinical presentation.
UR - http://www.scopus.com/inward/record.url?scp=85144066227&partnerID=8YFLogxK
U2 - 10.1111/ijd.16549
DO - 10.1111/ijd.16549
M3 - Review article
C2 - 36512719
AN - SCOPUS:85144066227
SN - 0011-9059
VL - 62
SP - 432
EP - 440
JO - International Journal of Dermatology
JF - International Journal of Dermatology
IS - 3
ER -