DNA sequence encoding a specific l-arabinose transporter, A cDNA molecule, a plasmid comprising the said DNA sequence, host cell transformed with such plasmid and application thereof

Isabel Maria Spencer Vieira Martins (Inventor), César Simões Da Fonseca (Inventor), Rita Baerbel Hahn-Haegerdal (Inventor)

Research output: PatentRegional/Other National Application

Abstract

The present invention refers to host cells genetically modified microorganisms by introducing a nucleic acid sequence encoding a specific L-arabinose transporter from yeast. The host cells are preferably those of an eukaryotic microorganism such as yeasts or filamentous fungi. The invention is useful for the complete use of sugar obtained from plant biomass and other ligno-cellulose materials of biotechnological importance in the production of biofuels, bulk and platform chemicals including ethanol, butanol, lactate, 1,4-diacids (succinate, fumaric, malic), glycerol, sorbitol, mannitol, xylitol/arabinitol, L-ascorbic acid, xylitol, hydrogen gas, 2,5-furan dicarboxylic acid, 3-hydroxy propionic acid, aspartic acid, glutaric acid, glutamic acid, itaconic acid, levulinic acid, and 3-hydroxybutyrolactone, fatty acids, fatty-derived molecules, isoprenoids, isoprenoid-derived molecules, alkanes, isopentanol, isoamylacetate, using genetically-modified microorganisms to consume and ferment L-arabinose in hexose and pentose mixtures resulting from renewable raw materials.
Original languageEnglish
Patent numberEP2167533
IPCC07K 14/ 40 A I
Priority date6/07/07
Filing date4/07/08
Publication statusPublished - 31 Mar 2010

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