Discovery of Novel Plant Peptides as Strong Inhibitors of Metalloproteinases

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Abstract

Five novel metalloproteinase protein inhibitors (MPIs) with molecular mass between 5.6 and 8.9 kDa and acid/neutral pI were detected in lupin seeds and exhibited strong inhibitory activities against thermolysin and/or gelatinase B. These novel peptides constitute not only the first MPIs described in plants but also the first plant peptides with inhibitory activity against a matrixin.
Original languageUnknown
Pages (from-to)543-551
JournalProtein And Peptide Letters
Volume16
Issue number5
DOIs
Publication statusPublished - 1 Jan 2009

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