TY - JOUR
T1 - Direct application of the INNO-LiPA Rif.TB line-probe assay for rapid identification of Mycobacterium tuberculosis complex strains and detection of rifampin resistance in 360 smear-positive respiratory specimens from an area of high incidence of multidrug-resistant tuberculosis
AU - Viveiros, Miguel
AU - Leandro, Clara
AU - Rodrigues, Liliana
AU - Almeida, Josefina
AU - Bettencourt, Rosário
AU - Couto, Isabel
AU - Carrilho, Lurdes
AU - Diogo, José
AU - Fonseca, Ana
AU - Lito, Luís
AU - Lopes, João
AU - Pacheco, Teresa
AU - Pessanha, Mariana
AU - Quirim, Judite
AU - Sancho, Luísa
AU - Salfinger, Max
AU - Amaral, Leonard
PY - 2005/9/1
Y1 - 2005/9/1
N2 - The INNO-LiPA Rif.TB assay for the identification of Mycobacterium tuberculosis complex strains and the detection of rifampin (RIF) resistance has been evaluated with 360 smear-positive respiratory specimens from an area of high incidence of multidrug-resistant tuberculosis (MDR-TB). The sensitivity when compared to conventional identification/culture methods was 82.2%, and the specificity was 66.7%; the sensitivity and specificity were 100.0% and 96.9%, respectively, for the detection of RIF resistance. This assay has the potential to provide rapid information that is essential for the effective management of MDR-TB.
AB - The INNO-LiPA Rif.TB assay for the identification of Mycobacterium tuberculosis complex strains and the detection of rifampin (RIF) resistance has been evaluated with 360 smear-positive respiratory specimens from an area of high incidence of multidrug-resistant tuberculosis (MDR-TB). The sensitivity when compared to conventional identification/culture methods was 82.2%, and the specificity was 66.7%; the sensitivity and specificity were 100.0% and 96.9%, respectively, for the detection of RIF resistance. This assay has the potential to provide rapid information that is essential for the effective management of MDR-TB.
UR - http://www.scopus.com/inward/record.url?scp=24744433767&partnerID=8YFLogxK
UR - https://jcm.asm.org/content/43/9/4880.long
U2 - 10.1128/JCM.43.9.4880-4884.2005
DO - 10.1128/JCM.43.9.4880-4884.2005
M3 - Article
C2 - 16145166
AN - SCOPUS:24744433767
SN - 0095-1137
VL - Vol. 43
SP - 4880
EP - 4884
JO - Journal Of Clinical Microbiology
JF - Journal Of Clinical Microbiology
IS - n.º 9
ER -