Diastolic dysfunction in hypertension

R. Nazário Leão; P. Marques da Silva

doi:10.1016/j.hipert.2017.01.001

Diastolic dysfunction in hypertension

R. Nazário Leão, P. Marques da Silva

NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)

Research output: Contribution to journal › Short survey › peer-review

9 Citations (Scopus)

Abstract

Hypertension and coronary heart disease, often coexisting, are the most common risk factors for heart failure. The progression of hypertensive heart disease involves myocardial fibrosis and alterations in the left ventricular geometry that precede the functional change, initially asymptomatic. The left ventricular diastolic dysfunction is part of this continuum being defined by the presence of left ventricular diastolic dysfunction without signs or symptoms of heart failure or poor left ventricular systolic function. It is highly prevalent in hypertensive patients and is associated with increased cardiovascular morbidity and mortality. Despite its growing importance in clinical practice it remains poorly understood. This review aims to present the epidemiological fundamentals and the latest developments in the pathophysiology, diagnosis and treatment of left ventricular diastolic dysfunction. © 2017 SEH-LELHA

Original language	English
Pages (from-to)	128-139
Number of pages	12
Journal	Hipertension y Riesgo Vascular
Volume	34
Issue number	3
DOIs	https://doi.org/10.1016/j.hipert.2017.01.001
Publication status	Published - Jul 2017

Keywords

Diastolic dysfunction
Heart failure with preserved ejection fraction
Hypertension
Hypertensive heart disease
Left Ventricular geometry

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title = "Diastolic dysfunction in hypertension",

abstract = "Hypertension and coronary heart disease, often coexisting, are the most common risk factors for heart failure. The progression of hypertensive heart disease involves myocardial fibrosis and alterations in the left ventricular geometry that precede the functional change, initially asymptomatic. The left ventricular diastolic dysfunction is part of this continuum being defined by the presence of left ventricular diastolic dysfunction without signs or symptoms of heart failure or poor left ventricular systolic function. It is highly prevalent in hypertensive patients and is associated with increased cardiovascular morbidity and mortality. Despite its growing importance in clinical practice it remains poorly understood. This review aims to present the epidemiological fundamentals and the latest developments in the pathophysiology, diagnosis and treatment of left ventricular diastolic dysfunction. {\textcopyright} 2017 SEH-LELHA",

keywords = "Diastolic dysfunction, Heart failure with preserved ejection fraction, Hypertension, Hypertensive heart disease, Left Ventricular geometry",

author = "{Naz{\'a}rio Le{\~a}o}, R. and {Marques da Silva}, P.",

year = "2017",

month = jul,

doi = "10.1016/j.hipert.2017.01.001",

language = "English",

volume = "34",

pages = "128--139",

journal = "Hipertension y Riesgo Vascular",

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T1 - Diastolic dysfunction in hypertension

AU - Nazário Leão, R.

AU - Marques da Silva, P.

PY - 2017/7

Y1 - 2017/7

N2 - Hypertension and coronary heart disease, often coexisting, are the most common risk factors for heart failure. The progression of hypertensive heart disease involves myocardial fibrosis and alterations in the left ventricular geometry that precede the functional change, initially asymptomatic. The left ventricular diastolic dysfunction is part of this continuum being defined by the presence of left ventricular diastolic dysfunction without signs or symptoms of heart failure or poor left ventricular systolic function. It is highly prevalent in hypertensive patients and is associated with increased cardiovascular morbidity and mortality. Despite its growing importance in clinical practice it remains poorly understood. This review aims to present the epidemiological fundamentals and the latest developments in the pathophysiology, diagnosis and treatment of left ventricular diastolic dysfunction. © 2017 SEH-LELHA

AB - Hypertension and coronary heart disease, often coexisting, are the most common risk factors for heart failure. The progression of hypertensive heart disease involves myocardial fibrosis and alterations in the left ventricular geometry that precede the functional change, initially asymptomatic. The left ventricular diastolic dysfunction is part of this continuum being defined by the presence of left ventricular diastolic dysfunction without signs or symptoms of heart failure or poor left ventricular systolic function. It is highly prevalent in hypertensive patients and is associated with increased cardiovascular morbidity and mortality. Despite its growing importance in clinical practice it remains poorly understood. This review aims to present the epidemiological fundamentals and the latest developments in the pathophysiology, diagnosis and treatment of left ventricular diastolic dysfunction. © 2017 SEH-LELHA

KW - Diastolic dysfunction

KW - Heart failure with preserved ejection fraction

KW - Hypertension

KW - Hypertensive heart disease

KW - Left Ventricular geometry

U2 - 10.1016/j.hipert.2017.01.001

DO - 10.1016/j.hipert.2017.01.001

M3 - Short survey

C2 - 28268171

SN - 1889-1837

VL - 34

SP - 128

EP - 139

JO - Hipertension y Riesgo Vascular

JF - Hipertension y Riesgo Vascular

IS - 3

ER -

Diastolic dysfunction in hypertension

Abstract

Keywords

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