@inbook{c4bbbd2af52645858014204e665d87ec,
title = "Dextran nanoparticles: Preparation and applications",
abstract = "Dextran nanoparticles are grabbing world-wide attention of scientists and technologists for their wide-ranging applications as biomaterials. Dextran, a type of α-glucan is the first commercialized bacterial exopolysaccharide that exhibits high biocompatibility and biodegradability features enabling a large array of applications. This chapter concisely compiles the chemical and enzymatic methods of synthesis, characteristics and myriad applications of dextran-based nanoparticles such as nanocarriers, bioimaging, drug delivery, nanobiosensors, and nanoscaffolds to mention a few. A comprehensive understanding of other dextran-based conjugates, derivatives, hydrogels and micelles being used as nanomedicine is also presented. Although literature reveals sporadic distribution of cytotoxicity studies of dextran-based nanoparticles, a detailed review is accounted for future scope of study. The chapter concludes with an emphasis on the paradigm shift in exploiting dextran for trending applications in nanobiotechnology.",
keywords = "Biomaterial, Cytotoxicity, Dextran, Nanomedicine, Nanoparticles, Synthesis",
author = "Ukkund, {Shareefraza J.} and Bhavna Alke and Taqui, {Syed N.} and Syed, {Usman T.}",
year = "2022",
month = jan,
day = "11",
doi = "10.1016/B978-0-12-822351-2.00019-X",
language = "English",
isbn = "978-0-12-822351-2",
series = "Micro and Nano Technologies",
publisher = "Elsevier",
pages = "1--31",
editor = "Jayachandran Venkatesan and Kim, {Se-Kwon } and Anil, {Sukumaran } and {P. D}, Rekha",
booktitle = "Polysaccharide Nanoparticles",
address = "Netherlands",
}