Development of Switchable "Smart" Biomaterials Using an Environmental Friendly Technology

Teresa Maria Alves Casimiro Ribeiro; Ana Isabel Nobre Martins Aguiar de Oliveira Ricardo

doi:10.1557/PROC-1220-BB01-07

Development of Switchable "Smart" Biomaterials Using an Environmental Friendly Technology

Teresa Maria Alves Casimiro Ribeiro, Ana Isabel Nobre Martins Aguiar de Oliveira Ricardo

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The possibility of using three dimensional porous networks as microreactors for synthesizing thermoresponsive polymers and hydrogels in a CO2 environment is an important breakthrough in the strategies to prepare smart films, membranes and porous bulky devices that undergo fast reversible changes in surface properties triggered by external stimuli. In situ synthesis of thermoresponsive polymers namely, poly(N-isopropylacrylamide) (PNIPAAm) and poly (N,N-diethylacrylamide) (PDEAAm) within chitosan (CHT), collagen (CLG) and chitosan-collagen (CHT:CLG) blended scaffolds were performed in order to further impregnate with model drugs. The performance of these switchable release devices was evaluated through the study of drug release kinetics as a function of temperature and pH. The same methodology was successfully applied to produce thermoresponsive polysulfone-based membranes.

Original language	Unknown
Title of host publication	2009 MRS Fall Meeting - Symposium BB – Green Chemistry in Research and Development of Advanced Materials
Place of Publication	n/d
Publisher	n/d
Pages	1220-BB01-07
DOIs	https://doi.org/10.1557/PROC-1220-BB01-07
Publication status	Published - 1 Jan 2010
Event	2009 MRS Fall Meeting - Duration: 1 Jan 2009 → …

Conference

Conference	2009 MRS Fall Meeting
Period	1/01/09 → …

Access to Document

10.1557/PROC-1220-BB01-07

Cite this

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title = "Development of Switchable {"}Smart{"} Biomaterials Using an Environmental Friendly Technology",

abstract = "The possibility of using three dimensional porous networks as microreactors for synthesizing thermoresponsive polymers and hydrogels in a CO2 environment is an important breakthrough in the strategies to prepare smart films, membranes and porous bulky devices that undergo fast reversible changes in surface properties triggered by external stimuli. In situ synthesis of thermoresponsive polymers namely, poly(N-isopropylacrylamide) (PNIPAAm) and poly (N,N-diethylacrylamide) (PDEAAm) within chitosan (CHT), collagen (CLG) and chitosan-collagen (CHT:CLG) blended scaffolds were performed in order to further impregnate with model drugs. The performance of these switchable release devices was evaluated through the study of drug release kinetics as a function of temperature and pH. The same methodology was successfully applied to produce thermoresponsive polysulfone-based membranes.",

keywords = "polymerization, environmentally benign, biomaterial",

author = "Ribeiro, {Teresa Maria Alves Casimiro} and Ricardo, {Ana Isabel Nobre Martins Aguiar de Oliveira}",

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doi = "10.1557/PROC-1220-BB01-07",

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Development of Switchable "Smart" Biomaterials Using an Environmental Friendly Technology. / Ribeiro, Teresa Maria Alves Casimiro ; Ricardo, Ana Isabel Nobre Martins Aguiar de Oliveira.

2009 MRS Fall Meeting - Symposium BB – Green Chemistry in Research and Development of Advanced Materials. n/d : n/d, 2010. p. 1220-BB01-07.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AB - The possibility of using three dimensional porous networks as microreactors for synthesizing thermoresponsive polymers and hydrogels in a CO2 environment is an important breakthrough in the strategies to prepare smart films, membranes and porous bulky devices that undergo fast reversible changes in surface properties triggered by external stimuli. In situ synthesis of thermoresponsive polymers namely, poly(N-isopropylacrylamide) (PNIPAAm) and poly (N,N-diethylacrylamide) (PDEAAm) within chitosan (CHT), collagen (CLG) and chitosan-collagen (CHT:CLG) blended scaffolds were performed in order to further impregnate with model drugs. The performance of these switchable release devices was evaluated through the study of drug release kinetics as a function of temperature and pH. The same methodology was successfully applied to produce thermoresponsive polysulfone-based membranes.

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