TY - JOUR
T1 - Development of poly(vinylidene fluoride)/ionic liquid electrospun fibers for tissue engineering applications
AU - Dias, J. C.
AU - Correia, Daniela C.
AU - Lopes, Ana C.
AU - Ribeiro, Sylvie
AU - Ribeiro, Clarisse
AU - Sencadas, Vitor
AU - Botelho, Gabriela
AU - Esperança, José Manuel Silva Simões
AU - Laza, J. M.
AU - Vilas, J. L.
AU - León, Luis M.
AU - Lanceros-Méndez, Senentxu
PY - 2016/5/1
Y1 - 2016/5/1
N2 - Electroactive electrospun fiber mat composites based on poly(vinylidene fluoride) (PVDF) with 5 and 10Â % of 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonyl)amide ([C2mim][NTf2]) ionic liquid (IL) were developed for potential applications in the biomedical area. The morphology and polymer crystalline phase content of the fibers were evaluated as a function of the processing conditions. Hydrophobic random and aligned fibers have been obtained with average fiber diameters between ~700 and 500Â nm, the smaller diameters corresponding to the aligned fiber mats. The results show that the charge structure of [C2mim][NTf2] induces the crystallization of the PVDF fibers in the piezoelectric β-phase with full crystallization in this phase for an ionic liquid content of 10Â wt%. Furthermore, the presence of the ionic liquid also increases the degree of crystallinity of the fibers. Thermal degradation studies show a single degradation process which is strongly influenced by the polymer–IL interactions. Finally, the non-cytotoxicity of the fiber mats indicates their suitability for biomedical applications.
AB - Electroactive electrospun fiber mat composites based on poly(vinylidene fluoride) (PVDF) with 5 and 10Â % of 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonyl)amide ([C2mim][NTf2]) ionic liquid (IL) were developed for potential applications in the biomedical area. The morphology and polymer crystalline phase content of the fibers were evaluated as a function of the processing conditions. Hydrophobic random and aligned fibers have been obtained with average fiber diameters between ~700 and 500Â nm, the smaller diameters corresponding to the aligned fiber mats. The results show that the charge structure of [C2mim][NTf2] induces the crystallization of the PVDF fibers in the piezoelectric β-phase with full crystallization in this phase for an ionic liquid content of 10Â wt%. Furthermore, the presence of the ionic liquid also increases the degree of crystallinity of the fibers. Thermal degradation studies show a single degradation process which is strongly influenced by the polymer–IL interactions. Finally, the non-cytotoxicity of the fiber mats indicates their suitability for biomedical applications.
UR - http://www.scopus.com/inward/record.url?scp=84957011816&partnerID=8YFLogxK
U2 - 10.1007/s10853-016-9756-3
DO - 10.1007/s10853-016-9756-3
M3 - Article
AN - SCOPUS:84957011816
VL - 51
SP - 4442
EP - 4450
JO - Journal of Materials Science
JF - Journal of Materials Science
SN - 0022-2461
IS - 9
ER -