Development of novel ionic liquids based on ampicillin

Luís Alexandre Almeida Fernandes Cobra Branco; I.M. Marrucho; João M. M.  Araújo; Luis Paulo Rebelo; Manuel Nunes da Ponte; Cristina Prudêncio; Zeljko Petrovski

doi:10.1039/c2md00269h

Development of novel ionic liquids based on ampicillin

Luís Alexandre Almeida Fernandes Cobra Branco, I.M. Marrucho, João M. M. Araújo, Luis Paulo Rebelo, Manuel Nunes da Ponte, Cristina Prudêncio, Zeljko Petrovski

Research output: Contribution to journal › Article › peer-review

107 Citations (Scopus)

Abstract

Novel ionic liquids containing ampicillin as an active pharmaceutical ingredient anion were prepared with good yields by using a new, efficient synthetic procedure based on the neutralization of a moderately basic ammonia solution of ampicillin with different organic cation hydroxides. The relevant physical and thermal properties of these novel ionic liquids based on ampicillin were also evaluated.

Original language	Unknown
Pages (from-to)	494-497
Journal	MedChemComm
Volume	3
Issue number	4
DOIs	https://doi.org/10.1039/c2md00269h
Publication status	Published - 1 Jan 2012

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10.1039/c2md00269h

Cite this

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title = "Development of novel ionic liquids based on ampicillin",

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AU - Branco, Luís Alexandre Almeida Fernandes Cobra

AU - Marrucho, I.M.

AU - Araújo, João M. M.

AU - Rebelo, Luis Paulo

AU - Nunes da Ponte, Manuel

AU - Prudêncio, Cristina

AU - Petrovski, Zeljko

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KW - EMERGENCE

KW - GERMANY

KW - SALTS

KW - ACTIVE PHARMACEUTICAL INGREDIENTS

KW - QUATERNARY AMMONIUM

KW - CHEMISTRY

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