TY - JOUR
T1 - Depression and multimorbidity - Results from a nationwide study
AU - Pedrosa, Bárbara
AU - Neto, Mariana
AU - Namorado, Sónia
AU - Leite, Andreia
N1 - Funding Information:
This study is included in the project ECOS COVID-19, which is funded by Portuguese national funds through the FCT - Foundation for Science and Technology, I.P., within the scope of project n°130 of the 1st edition of the special support Research 4 COVID-19.
Funding Information:
This study was approved by the Ethics Committee of the Portuguese National Institute of Health Doctor Ricardo Jorge. Informed consent was obtained from every participant and data confidentiality was guaranteed. The data are not publicly available due to privacy or ethical restrictions. This study was conducted using secondary data collected as part of the ECOS study of the National Institute of Health Doctor Ricardo Jorge. ECOS data are available to investigators outside the ECOS team after request and approval by the National Institute of Health Doctor Ricardo Jorge Ethical Committee.
Publisher Copyright:
© 2022 Asociación Universitaria de Zaragoza para el Progreso de la Psiquiatría y la Salud Mental
PY - 2023/4
Y1 - 2023/4
N2 - Background and objectives: Most studies concerning the relationship between depression and chronic physical disease focused on a single physical disease and did not consider multimorbidity or depression severity. We aimed to characterize this relationship considering chronic physical diseases’ type and number, and depression severity. Methods: We undertook a cross-sectional study, using data from a phone household panel, with “chronic physical disease” as the exposure and “depression” as the outcome. The sample is representative of the Portuguese population. Adjusted logistic and multinomial regression analyses were conducted between depression presence/severity and chronic physical disease presence/type/number. Odds ratio and 95% confidence intervals adjusted for possible confounders were calculated. Results: 1027 individuals were included. Of the population, 8.9% had depression and 72.1% had at least one chronic physical disease. There was no statistically significant relationship between depression and physical disease in general (OR=1.68 [CI95%:0.55, 5.15]), but there was with allergy (OR=2.08 [CI95%:1.02, 4.25]) and COPD (OR=3.04 [CI95%:1.21, 7.61]). The risk of depression was smaller with two physical diseases (vs. three or more, OR=0.32 [CI95%:0.15, 0.68]). Conclusions: A relationship between COPD, allergy and a higher number of physical diseases and depression was observed. Clinicians should be aware of these relationships. Evaluating the presence of depression in people with multimorbidity, COPD and allergy is recommended.
AB - Background and objectives: Most studies concerning the relationship between depression and chronic physical disease focused on a single physical disease and did not consider multimorbidity or depression severity. We aimed to characterize this relationship considering chronic physical diseases’ type and number, and depression severity. Methods: We undertook a cross-sectional study, using data from a phone household panel, with “chronic physical disease” as the exposure and “depression” as the outcome. The sample is representative of the Portuguese population. Adjusted logistic and multinomial regression analyses were conducted between depression presence/severity and chronic physical disease presence/type/number. Odds ratio and 95% confidence intervals adjusted for possible confounders were calculated. Results: 1027 individuals were included. Of the population, 8.9% had depression and 72.1% had at least one chronic physical disease. There was no statistically significant relationship between depression and physical disease in general (OR=1.68 [CI95%:0.55, 5.15]), but there was with allergy (OR=2.08 [CI95%:1.02, 4.25]) and COPD (OR=3.04 [CI95%:1.21, 7.61]). The risk of depression was smaller with two physical diseases (vs. three or more, OR=0.32 [CI95%:0.15, 0.68]). Conclusions: A relationship between COPD, allergy and a higher number of physical diseases and depression was observed. Clinicians should be aware of these relationships. Evaluating the presence of depression in people with multimorbidity, COPD and allergy is recommended.
KW - Chronic physical disease
KW - Depression
KW - Multimorbidity
UR - http://www.scopus.com/inward/record.url?scp=85139662976&partnerID=8YFLogxK
U2 - 10.1016/j.ejpsy.2022.09.004
DO - 10.1016/j.ejpsy.2022.09.004
M3 - Article
AN - SCOPUS:85139662976
SN - 0213-6163
VL - 37
SP - 92
EP - 99
JO - European Journal of Psychiatry
JF - European Journal of Psychiatry
IS - 2
ER -