@article{145785a9c0e34783b5b1eb13e64fa50b,
title = "Data on metabolic profile of insulin-degrading enzyme knockout mice",
abstract = "Insulin-degrading enzyme (IDE) degrades and inactivates bioactive peptides such as insulin. As insulin is a master regulator of glucose homeostasis, lack of IDE is expected to have a profound impact on both insulin and glucose levels. This article shares data on glucose and insulin homeostasis of control, heterozygous and knockout mice for Ide after 18 weeks of a normal chow diet. This data article is related to a research article entitled “Knockout of insulin-degrading enzyme leads to mice testicular morphological changes and impaired sperm quality” (Meneses et al., 2019).",
author = "Borges, {Diego O.} and Meneses, {Maria Jo{\~a}o} and Dias, {T{\^a}nia R.} and Martins, {F{\'a}tima O.} and Oliveira, {Pedro F.} and Alves, {Marco G.} and Macedo, {M. Paula}",
note = "Funding Information: This work was supported by FEDER funds POCI - COMPETE 2020 , Portugal: Project POCI-01-0145-FEDER-007491 ; and by “ Funda{\c c}{\~a}o para a Ci{\^e}ncia e a Tecnologia ” – FCT to MJM ( PD/BD/114256/2016 ); TRD ( SFRH/BD/109284/2015 ); PFO ( PTDC/BBB-BQB/1368/2014 ; IFCT2015); MPM ( PTDC/DTP-EPI/0207/2012 ; PTDC/BIM-MET/2115/2014 ); MGA ( PTDC/BIM-MET/4712/2014 ; IFCT2015); iNOVA4Health ( UID/Multi/04462/2013 ); and UMIB ( PEst-OE/SAU/UI0215/2014 ). Funding Information: This work was supported by FEDER funds POCI - COMPETE 2020, Portugal: Project POCI-01-0145-FEDER-007491; and by “Funda{\c c}{\~a}o para a Ci{\^e}ncia e a Tecnologia” – FCT to MJM (PD/BD/114256/2016); TRD (SFRH/BD/109284/2015); PFO (PTDC/BBB-BQB/1368/2014; IFCT2015); MPM (PTDC/DTP-EPI/0207/2012; PTDC/BIM-MET/2115/2014); MGA (PTDC/BIM-MET/4712/2014; IFCT2015); iNOVA4Health (UID/Multi/04462/2013); and UMIB (PEst-OE/SAU/UI0215/2014). Publisher Copyright: {\textcopyright} 2019 The Authors",
year = "2019",
month = aug,
doi = "10.1016/j.dib.2019.104023",
language = "English",
volume = "25",
journal = "Data in brief",
issn = "2352-3409",
publisher = "Elsevier BV",
}