Data on metabolic profile of insulin-degrading enzyme knockout mice

Diego O. Borges, Maria João Meneses, Tânia R. Dias, Fátima O. Martins, Pedro F. Oliveira, Marco G. Alves, M. Paula Macedo

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Abstract

Insulin-degrading enzyme (IDE) degrades and inactivates bioactive peptides such as insulin. As insulin is a master regulator of glucose homeostasis, lack of IDE is expected to have a profound impact on both insulin and glucose levels. This article shares data on glucose and insulin homeostasis of control, heterozygous and knockout mice for Ide after 18 weeks of a normal chow diet. This data article is related to a research article entitled “Knockout of insulin-degrading enzyme leads to mice testicular morphological changes and impaired sperm quality” (Meneses et al., 2019).

Original languageEnglish
Article number104023
JournalData in brief
Volume25
DOIs
Publication statusPublished - 1 Aug 2019

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Insulysin
Metabolome
Knockout Mice
Insulin
Glucose
Homeostasis
Spermatozoa
Diet
Peptides
Research

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Data on metabolic profile of insulin-degrading enzyme knockout mice. / Borges, Diego O.; Meneses, Maria João; Dias, Tânia R.; Martins, Fátima O.; Oliveira, Pedro F.; Alves, Marco G.; Macedo, M. Paula.

In: Data in brief, Vol. 25, 104023, 01.08.2019.

Research output: Contribution to journalArticle

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AU - Alves, Marco G.

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