TY - CONF
T1 - Cytotoxicity analyses of environmental samples
T2 - 17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022
AU - Viegas, Carla
AU - Cervantes, Renata
AU - Gomes, Bianca
AU - Dias, Marta
AU - Viegas, Susana
AU - Caetano, Liliana Aranha
N1 - Funding Information:
This work was supported by: Instituto Politécnico de Lisboa, Lisbon, Portugal, “Waste Workers' Exposure to Bioburden through Filtering Respiratory Protective Devices” (IPL/2018/WasteFRPD_ESTeSL). H&TRC authors gratefully acknowledge the FCT/MCTES national support through the UIDB/05608/2020 and UIDP/05608/2020.
Funding Information:
This work was supported by: Instituto Politécnico de Lisboa, Lisbon, Portugal, “Waste Workers’ Exposure to Bioburden through Filtering Respiratory Protective Devices” (IPL/2018/WasteFRPD_ESTeSL). H&TRC authors gratefully acknowledge the FCT/MCTES national support through the UIDB/05608/2020 and UIDP/05608/2020.
Publisher Copyright:
© 2022 17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022. All rights reserved.
PY - 2022
Y1 - 2022
N2 - Analyzing environmental complex matrices can help to unveil the toxicity of multiple contaminants in occupational environments and to estimate health risks by co-exposures. Here, the in vitro toxicity of samples collected in animal feed industries, waste sorting plants, and animal production facilities is compared. Air and passive samples (e.g., respiratory masks and gloves) had been extracted with 0.9% NaCl and incubated with human and mammal cells. High cytotoxicity (determined by the MTT assay) and pro-inflammatory effects (determined by cytokine quantification) were observed in different occupational environments. These findings highlight the importance of performing cytotoxicity analyses in environmental samples.
AB - Analyzing environmental complex matrices can help to unveil the toxicity of multiple contaminants in occupational environments and to estimate health risks by co-exposures. Here, the in vitro toxicity of samples collected in animal feed industries, waste sorting plants, and animal production facilities is compared. Air and passive samples (e.g., respiratory masks and gloves) had been extracted with 0.9% NaCl and incubated with human and mammal cells. High cytotoxicity (determined by the MTT assay) and pro-inflammatory effects (determined by cytokine quantification) were observed in different occupational environments. These findings highlight the importance of performing cytotoxicity analyses in environmental samples.
KW - Air sampling
KW - Cytotoxicity
KW - management
KW - Passive sampling
KW - Risk characterization
UR - http://www.scopus.com/inward/record.url?scp=85159231819&partnerID=8YFLogxK
M3 - Paper
AN - SCOPUS:85159231819
Y2 - 12 June 2022 through 16 June 2022
ER -
