Cytochromes c′ are heme proteins presumably involved in electron transport and the name cytochrome c′ is used to distinguish these high‐spin heme proteins from the low‐spin mitochondrial cytochromes c. The heme group is covalently bound by thioether bonds between the two vinyl groups of the heme and the two cysteinyl side chains in a sequence, ‐Cys‐X‐Y‐Cys‐His‐, typical of cytochromes c. The histine occupies the fifth axial coordination position. Most cytochromes c′ are isolated as homodimers of ca 2 × 14 kDa and each monomer consists of an anti‐parallel four‐α‐helical bundle, which defines the heme‐binding pocket.
Original languageEnglish
Title of host publicationHandbook of Metalloproteins
EditorsAlbrecht Messerschmidt, Robert Huber, Thomas Poulas, Karl Wieghardt, Mirek Cygler, Wolfram Bode
PublisherJohn Wiley & Sons, Ltd.
ISBN (Electronic)0470028637, 9780470028636
ISBN (Print)047086981X, 9780470869819
Publication statusPublished - 15 Apr 2006


Dive into the research topics of 'Cytochrome c`'. Together they form a unique fingerprint.

Cite this