@article{270ca0312e9d444f86b32ff65cd86a13,
title = "Copper Catalyzed Regioselective Intramolecular Oxidative a-Functionalization of Tertiary Amines: An Efficient Synthesis of Dihydro-1,3-Oxazines",
abstract = "Traffic control: The hydroxy functional group directs the α-functionalization of tertiary amines, synthesizing 1,3-oxazines by C-O bond formation. Reaction occurs with both benzylic and non-benzylic amines. In the case of naphthoxazine synthesis, 100 % diastereoselectivity was observed. A tentative two-pathway mechanism is proposed for the reaction.",
keywords = "C-H activation, copper catalysis, diastereoselectivity, regioselectivity, C-O bond formation, C-H activation, C-O bond formation, copper catalysis, diastereoselectivity, regioselectivity",
author = "Deb, {Mohit L.} and Dey, {Suvendu S.} and Bento, {Isabel Maria} and Barros, {Maria Teresa} and Christopher Maycock",
note = "This study was supported by FCT (Fundacao para a Ciencia e a Tecnologia) under the project POCI/HAR/55882/2004 and UID/EAT/00729/2013. The PhD grant SFRH/BD/85329/2012 by FCT to Filipa Lopes is also acknowledged. The authors are grateful to Rosario Gil and Camara Municipal do Barreiro for their help in accessing the archaeological glass collection. We would like to thank in particular Manuela Almeida Ferreira for her valuable support in this project.",
year = "2013",
month = sep,
doi = "10.1002/anie.201304654",
language = "English",
volume = "52",
pages = "9791–9795",
journal = "Angewandte Chemie (International ed. in English)",
issn = "1521-3773",
publisher = "Wiley",
number = "37",
}