Cognitive disorders in patients with chronic kidney disease: specificities of clinical assessment

Marion Pépin, Ana Carina Ferreira, Mustafa Arici, Maie Bachman, Michelangela Barbieri, Inga Arune Bumblyte, Sol Carriazo, Pilar Delgado, Liliana Garneata, Konstantinos Giannakou, Olivier Godefroy, Tomasz Grodzicki, Aleksandra Klimkowicz-Mrowiec, Justina Kurganaite, Sophie Liabeuf, Carmen Antonia Mocanu, Giuseppe Paolisso, Goce Spasovski, Evgueniy Stefanov Vazelov, Davide ViggianoCarmine Zoccali, Ziad A Massy, Andrzej Więcek

Research output: Contribution to journalArticlepeer-review

Abstract

Neurocognitive disorders are frequent among chronic kidney disease (CKD) patients. Identifying and characterizing cognitive impairment (CI) can help to assess the ability of adherence to CKD risk reduction strategy, identify potentially reversible causes of cognitive decline, modify pharmacotherapy, educate the patient and caregiver and provide appropriate patient and caregiver support. Numerous factors are associated with the development and progression of CI in CKD patients and various conditions can influence the results of cognitive assessment in these patients. Here we review clinical warning signs that should lead to cognitive screening; conditions frequent in CKD at risk to interfere with cognitive testing or performance, including specificities of cognitive assessment in dialysis patients or after kidney transplantation; and available tests for screening and observed cognitive patterns in CKD patients.

Original languageEnglish
Pages (from-to)ii23-ii32
JournalNephrology Dialysis Transplantation
Volume37
Issue number2
Early online date31 Oct 2021
DOIs
Publication statusPublished - 28 Dec 2021

Keywords

  • chronic kidney disease
  • clinical assessment
  • cognitive impairment
  • cognitive screening test
  • comprehensive battery

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