@article{dc18db43d4304d228cad14313a87b10d,
title = "Clinical implications of molecular markers in follicular cell-derived thyroid cancer",
abstract = "The increasing use/applications of molecular biology techniques have provided new insights on the genetic changes that underlie carcinogenesis and tumor progression in thyroid cancer. Molecular analysis may improve the histopathologic evaluation of follicular cell-derived thyroid carcinoma, not only elucidating some unresolved problems related to the diagnosis and disease prognosis, but also by improving patient management. Besides increasing our comprehension of cancer biology, either genetic alterations or gene expression profiles implicated in thyroid carcinogenesis shed new light on innovative diagnostic procedures as well as on targeted therapies.",
keywords = "BRAF MUTATIONS, diagnosis, thyroid cancerFINE-NEEDLE-ASPIRATION, genetic alteration, targeted therapy, RET/PTC GENE REARRANGEMENTS, NUCLEAR-DNA CONTENT, GENOME-WIDE APPRAISAL, HIGH PREVALENCE, gene-expression profiling, CYCLIN D1, PAPILLARYCARCINOMAS, RAS MUTATIONS, AGGRESSIVE TUMORPHENOTYPES, molecularmarker, prognosis",
author = "Pinto, {Ant{\'o}nio E.} and Leite, {Valeriano Alberto Pais Horta} and Soares, {Jorge Oliveira}",
note = "Expert Rev. Mol. Diagn. Pinto, Antonio E. Leite, Valeriano Soares, JorgeHead & Neck, Endocrinology and Pathology departments at the Institution The authors thank the colleagues who work on Head & Neck, Endocrinology and Pathology departments at the Institution for their collaboration and support. We would like to apologize to the authors whose works were not cited because of space constraints. 160 EXPERT REVIEWS LONDON 512PA",
year = "2009",
month = oct,
doi = "10.1586/erm.09.54",
language = "English",
volume = "9",
pages = "679--694",
journal = "Expert Review Of Molecular Diagnostics",
issn = "1473-7159",
publisher = "Expert Reviews",
number = "7",
}
