Choroidal binarization analysis: clinical application

Sara Crisostomo, Joana Cardigos, Diogo Hipólito Fernandes, Maria Elisa Luís, Ricardo Figueiredo, Nuno Moura-Coelho, João Paulo Cunha, Luís Abegão Pinto, Joana Ferreira

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)


Introduction: Image processing of optical coherence tomography scans through binarization techniques represent a non-invasive way to separately asses and measure choroidal components, in vivo. In this review, we systematically search the scientific literature regarding binarization studies published so far. Methods: A systematic research was conducted at PubMed database, including English literature articles for all of the following terms in various combinations: binarization, choroid/al, enhanced depth spectral domain/swept source optic coherence tomography, and latest publications up to November 2018 were reviewed. Results: Thirty-seven articles were included and analyzed regarding studied disease, binarization method, studied variables, and outcomes. Most of the studies have focused on the more common retinal pathologies, such as age-related macular degeneration, central serous chorioretinopathy and diabetic retinopathy but binarization techniques have also been applied to the study of choroidal characteristics in ocular inflammatory diseases, corneal dystrophies and in postsurgical follow-up. Advantages and disadvantages of binarization techniques are also discussed. Conclusion: Binarization of choroidal images seems to represent a promising approach to study choroid subcomponents in an increasingly detailed manner.

Original languageEnglish
Pages (from-to)2947-2973
JournalInternational Ophthalmology
Issue number12
Publication statusPublished - Dec 2019


  • Binarization
  • Choroid
  • Choroidal imaging
  • Optic coherence tomography


Dive into the research topics of 'Choroidal binarization analysis: clinical application'. Together they form a unique fingerprint.

Cite this