Chondrosarcoma of the hyoid bone: Case report and review of the literature

D. Amaral, C. Zagalo, C. Cardina, P. Vera-Cruz

Research output: Contribution to journalArticlepeer-review


INTRODUCTION: Chondrosarcomas are cartilaginous tumors that range from low-grade tumors with low metastatic potential to high-grade aggressive tumors with premature and high metastatic rate. Low-grade types have few karyotype abnormalities and are near-diploid, while high-grade chondrosarcomas originate from complex karyotypes and are aneuploid. The most common karyotype aberrations found include 12q13-15 and 9p21 rearrangements. Here, it is presented a case of chondrosarcoma of the hyoid bone with its image, surgical procedure and pathological correlation as well as a review of the literature.

CASE PRESENTATION: A sixty-three year old man presented with a large cervical mass located at submental level. The CT scan revealed a voluminous and well-limited mass of 5 x 4 x 3 cm located in the suprahyoid region. The operative finding revealed a grade 2 chondrosarcoma originating from the hyoid bone.

DISCUSSION: Chondrosarcoma of the. hyoid bone is a rare pathology, thus making it difficult to diagnose. Fine needle biopsies have high diagnostic accuracy, although correct grading is only obtained 46% of the time. CT scan is the golden standard to characterize tumor extension and origin. Surgical excision is the treatment of choice for chondrosarcoma.

Original languageEnglish
Pages (from-to)77-80
Number of pages4
JournalRevue de laryngologie - otologie - rhinologie
Issue number2
Publication statusPublished - 1 Jan 2015


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