@article{2e9f89718995447a91cafcc6e144243a,
title = "Chiral Aziridination of Olefins Using a Chiral Sulfinamide as the Nitrogen Source",
abstract = "Chiral aziridination of cyclic alpha-bromoenones is achieved by the use of the lithium salt of (S-S)-(+)-p-toluenesulfinamide, which leads to products with diastereomeric excesses in the range of 30-65% using a simple protocol. A key factor associated with chiral induction is the incorporation of the reacting olefin in a cycle, indicating the importance of conformational restriction in the reacting double bond.",
keywords = "chirality, additions, phosphate, bromamine-t, imines, tamiflu, enones, cyclization, asymmetric-synthesis, cyclizations, aziridination, aminations, Michael, induced, transformations, oseltamivir, carbonyl-compounds, diastereoselective, rearrangement",
author = "Vasco Bonif{\'a}cio and Lobo, {Ana Maria F{\'e}lix Trindade} and Prabhakar, {Alberto Sundaresan}",
year = "2010",
month = jan,
day = "1",
doi = "10.1055/s-0029-1218545",
language = "Unknown",
volume = "n/d",
pages = "145--149",
journal = "Synlett",
issn = "0936-5214",
publisher = "Georg Thieme Verlag",
number = "1",
}