Chagas disease in the state of amazonas: History, epidemiological evolution, risks of endemicity and future perspectives

Maria das Graças Vale Barbosa, João Marcos Bemfica Barbosa Ferreira, Ana Ruth Lima Arcanjo, Rosa Amélia Gonçalves Santana, Laylah Kelre Costa Magalhães, Laise Kelma Costa Magalhães, Daniel Testa Mota, Nelson Ferreira Fé, Wuelton Marcelo Monteiro, Henrique Silveira, Jorge Augusto Oliveira De Guerra

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)
16 Downloads (Pure)


Chagas disease (CD) is a parasitic infection that originated in the Americas and is caused by Trypanosoma cruzi. In the last few years, the disease has spread to countries in North America, Asia and Europe due to the migration of Latin Americans. In the Brazilian Amazon, CD has an endemic transmission, especially in the Rio Negro region, where an occupational hazard was described for piaçaveiros (piassaba gatherers). In the State of Amazonas, the fi rst chagasic infection was reported in 1977, and the fi rst acute CD case was recorded in 1980. After initiatives to integrate acute CD diagnostics with the malaria laboratories network, reports of acute CD cases have increased. Most of these cases are associated with oral transmission by the consumption of contaminated food. Chronic cases have also been diagnosed, mostly in the indeterminate form. These cases were detected by serological surveys in cardiologic outpatient clinics and during blood donor screening. Considering that the control mechanisms adopted in Brazil’s classic transmission areas are not fully applicable in the Amazon, it is important to understand the disease behavior in this region, both in the acute and chronic cases. Therefore, the pursuit of control measures for the Amazon region should be a priority given that CD represents a challenge to preserving the way of life of the Amazon’s inhabitants.

Original languageEnglish
Pages (from-to)27-33
Number of pages7
JournalRevista Da Sociedade Brasileira De Medicina Tropical
Publication statusPublished - 2015


  • Brazilian Amazon
  • Chagas’ disease
  • State of Amazonas
  • Trypanosoma cruzi


Dive into the research topics of 'Chagas disease in the state of amazonas: History, epidemiological evolution, risks of endemicity and future perspectives'. Together they form a unique fingerprint.

Cite this