TY - PAT
T1 - Cationic core-shell polymers
AU - Bonifácio, Vasco Daniel Bigas
AU - Mil-Homens, Dalila Madeira do Nascimento
AU - Pinto, Sandra Cistina Nunes Trigo Fernandes
AU - Pires, Rita Figueiredo
AU - Fialho, Arsénio do Carmo Sales Mendes
AU - Bernardes, Nuno Filipe Santos
AU - Ricardo, Ana Isabel Nobre M.A. de Oliveira
PY - 2022/4/7
Y1 - 2022/4/7
N2 - The present invention relates to novel cationic core-shell polymers comprising a core consisting of a polyurea dendrimer of generation n conjugated to a layer consisting of a cationic olygoethyleneimine polymer with a polymerization degree r, which are synthesized in a sustainable, simple and low-cost manner. In addition to their low toxicity and low hemolysis, these polymers also have an inherent biological activity. These polymers may also be included in formulations. The polymers of the present invention and formulations comprising same can be used in the treatment of infections caused by pathogenic bacteria and fungi and also in the treatment of several kinds of cancer.
AB - The present invention relates to novel cationic core-shell polymers comprising a core consisting of a polyurea dendrimer of generation n conjugated to a layer consisting of a cationic olygoethyleneimine polymer with a polymerization degree r, which are synthesized in a sustainable, simple and low-cost manner. In addition to their low toxicity and low hemolysis, these polymers also have an inherent biological activity. These polymers may also be included in formulations. The polymers of the present invention and formulations comprising same can be used in the treatment of infections caused by pathogenic bacteria and fungi and also in the treatment of several kinds of cancer.
M3 - International PCT application
M1 - WO2022071819
Y2 - 2021/10/01
ER -
